Tests a sacral nerve stimulation device in adults with ulcerative colitis
Tests a nerve stimulation device for long-term use in people with ulcerative colitis.
Plain-language title generated from the registry record
Registry title: Long-term Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis
Key facts
- Where
- Xi'an, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07114159, who can take part
Where in China
- Xijing hospitalXi'an, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Xijing Hospital
- Trial code
- NCT07114159
- Record updated
- 11 August 2025
- Original description
Although the incidence of inflammatory bowel disease is stable in North American and European countries, the incidence of inflammatory bowel disease is increasing in newly industrialized countries, especially in China. The treatment drugs for ulcerative colitis include 5-aminosalicylic acid (5-ASA), glucocorticoids, immunosuppressants, and biological agents. The aim of this clinical trial is to evaluate the long-term safety and efficacy of sacral nerve stimulation in patients with ulcerative colitisRead full original descriptionShow less
An Open-label Clinical Trial to Evaluate the Long-term Safety and Efficacy of Sacral Nerve Stimulation in Patients With Ulcerative Colitis
Although the incidence of inflammatory bowel disease is stable in North American and European countries, the incidence of inflammatory bowel disease is increasing in newly industrialized countries, especially in China. The treatment drugs for ulcerative colitis include 5-aminosalicylic acid (5-ASA), glucocorticoids, immunosuppressants, and biological agents. The aim of this clinical trial is to evaluate the long-term safety and efficacy of sacral nerve stimulation in patients with ulcerative colitis
Inclusion: age 18-65 years; ulcerative colitis diagnosed for at least 3 mouths; Mayo score 6-12, Mayo endoscopic score 2-3 points; resistant to medical treatment.
Exclusion: Treatment-naive ulcerative colitis (no previous treatment); Currently taking any biologicals; Previous surgical treatment or severe colitis at imminent risk of surgery; Other systemic diseases; Acute severe ulcerative colitis; infective colitis; Pregnancy and lactation.