Tests rose scent exposure in people with epilepsy during hospital monitoring
Tests whether rose scent exposure affects breathing pauses during seizures in adults with epilepsy.
Plain-language title generated from the registry record
Registry title: Effect of Rose Odor Exposure on Ictal Apnea
Key facts
- Where
- Nashville, United StatesSee the site
- Phase
- Early phase 1
Where in United States
- Vanderbilt University Medical CenterNashville, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Vanderbilt University Medical Center
- Trial code
- NCT07116421
- Record updated
- 11 June 2026
- Original description
This study will investigate the potential benefits of rose scent in reducing the risk of Sudden Unexpected Death in Epilepsy (SUDEP) in patients with epilepsy. Participants will engage in their routine inpatient observational EEG monitoring for 24 hours followed by an additional 24 hours of observational EEG monitoring with continuous exposure to rose scent, during which an essential oil diffusor with rose scent will be placed in their hospital room. During these 48 total hours of the study, participants will wear a respiratory monitoring belt across their upper chest to measure their breathing.Read full original descriptionShow less
Effect of 2-phenylethanol Odor Exposure on Ictal Apneic Episode Occurrence Rate in Patients With Epilepsy
This study will investigate the potential benefits of rose scent in reducing the risk of Sudden Unexpected Death in Epilepsy (SUDEP) in patients with epilepsy. Participants will engage in their routine inpatient observational EEG monitoring for 24 hours followed by an additional 24 hours of observational EEG monitoring with continuous exposure to rose scent, during which an essential oil diffusor with rose scent will be placed in their hospital room. During these 48 total hours of the study, participants will wear a respiratory monitoring belt across their upper chest to measure their breathing.
Potential risks include distress or discomfort when smelling the rose scent used in the study, a physical reaction to the rose scent, and discomfort or feelings of restrictiveness when wearing the respiratory monitoring belt. The total time commitment of the study is 48 consecutive hours over the course of the participants' inpatient EMU stay, during which there will be no restrictions on daily activities during the standard inpatient EMU admission except that participants must wear their respiratory belt for a majority of this 2-day period.
Inclusion: Adult epilepsy patients over the age of 18; Admission to the inpatient epilepsy monitoring unit (EMU) at Vanderbilt University Medical Center (VUMC); Undergoing observational EEG monitoring without treatment involving seizure medication changes or other interventions for at least 48 hours.
Exclusion: Patients receiving EEG monitoring without interventions from baseline for less than 48 hours; Patients who are not receiving EEG monitoring as a part of their inpatient admission; Patients under the age of 18.