Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy
Key facts
- Who runs it
- Kocaeli University
- Where
- Kocaeli, TürkiyeSee the site
- Trial code
- Status
- Recruiting
- People taking part
- 36 people, planned
- Started
- 15 Dec 2025
- Planned end
- 30 Jun 2026
- Type of study
- Observational
- Record updated
- 3 February 2026
Who can take part
- Age
- 4 years to 18 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 12 criteriaShow less
Who can take part
- Diagnosis of spastic cerebral palsy (SCP) according to the criteria defined by Rosenbaum et al. (2007)
- Age between 4 and 18 years
- Gross Motor Function Classification System (GMFCS) Level I, II, or III
- Manual Ability Classification System (MACS) Level I, II, III, or IV
Who cannot take part
- Current treatment with oral or intrathecal antispastic medications
- Diagnosis of neuromuscular disorders other than cerebral palsy (e.g., hereditary neuropathy, myopathy)
- History of orthopedic surgery or selective dorsal rhizotomy involving the target muscles
- Acute infection, febrile illness, or severe systemic disease (e.g., advanced heart failure, respiratory insufficiency) that may compromise the safety of assessments
- Non-spastic types of cerebral palsy (e.g., dyskinetic, ataxic)
- Presence of muscle contractures or fixed deformities in the limbs selected for ultrasound and clinical assessment
- Cognitive or behavioral impairments that prevent cooperation during ultrasound or clinical evaluation
- Botulinum toxin-A (BoNT-A) injection applied to the target muscles within the last 6 months
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 4 and 18 years old?
Where in Türkiye
- Kocaeli University Faculty of MedicineKocaeli, TürkiyeContact: Mustafa Kadıoğlu, MDTaking people
About the trial
What the trial wants to find out
This study focuses on children with spastic cerebral palsy and aims to examine how muscle morphology and tissue characteristics, as assessed by ultrasound, may relate to functional motor abilities. It is designed as a prospective, cross-sectional, observational study. Planned ultrasound-based assessments include parameters such as muscle thickness, pennation angle, fascicle length, echo intensity, tissue stiffness (via shear wave elastography), and microvascular flow (via superb microvascular imaging). These measurements are intended to be compared with standard clinical evaluations, including the GMFCS, GMFM-66, MAS, MACS, and Tardieu Scale. The study seeks to contribute to a better understanding of the relationship between muscle architecture and functional outcomes, with the goal of generating insights that may inform individualized rehabilitation planning.
The group in the trial
- Spastic CP Cohort
Ambulatory children with spastic cerebral palsy classified within GMFCS levels I to III. Participants undergo clinical and ultrasound-based assessments to evaluate muscle morphology, functional properties, and their relationship with motor function.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Evaluation of the Relationship Between Ultrasonographic Muscle Morphology, Functional Properties, and Clinical Parameters in Children With Spastic Cerebral Palsy
- Fit questions
- Built from NCT07118228, who can take part
- Record updated
- 3 February 2026