Personality Traits and Recovery After Acquired Brain Injury or Stroke
Studies whether personality before injury affects recovery in adults with brain injury or stroke.
Plain-language title generated from the registry record
Registry title: Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
Key facts
- Where
- Verona, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07119827, who can take part
Where in Italy
- Sezione medicina fisica e riabilitativa dipartimento di neuroscienze, veronaVerona, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universita di Verona
- Trial code
- NCT07119827
- Record updated
- 2 July 2026
- Original description
This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke.Read full original descriptionShow less
Neuropsychology and Personality: Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke.
The secondary aims are to assess the effects of premorbid personality on the sort- and long-term recovery in autonomy (disability), cognitive functions, psycho-behavioral functioning, motor skills, and social participation. Evaluate the incidence of premorbid personality alterations. Investigate personality changes 12-18 months after the neurological event.
Inclusion: diagnosis of one of the following two conditions:; Severe Acquired Brain Injury (sABI) of traumatic or non-traumatic etiology; the term sABI includes acute brain injuries of traumatic or non-traumatic origin (vascular, infectious, metabolic, or anoxic), in which the patient initially presents with a coma state (Glasgow Coma Scale - GCS less than 8) and simultaneously exhibits motor, sensory, cognitive, and/or behavioral impairments; Ischemic or hemorrhagic stroke without features of Severe Acquired Brain Injury (sABI) (Glasgow Coma Scale [GCS] score ≥ 8 and no alteration of consciousness); Time from injury between:; 7 and 90 days for Severe Acquired Brain Injury (sABI) patients; 3 and 30 days for stroke patients; Level of Cognitive Functioning (LCF) score ≥ 6 for sABI patients; Signed informed consent for study participation; Presence of a support family member (caregiver) able to assist with completing the personality questionnaire (HEXACO Adjective Scale, HAS).
Exclusion: Pre-existing neurological pathology; Severe aphasia or severe inattention that precludes administration of the tests required by the protocol, as identified during cognitive screening; Patients with a language barrier due to insufficient proficiency in Italian; Particularly vulnerable populations:; The following patients will be excluded from the study: patients in emergency situations.