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Studies a gene variant and risk of open angle glaucoma

Looks at whether an MMP-9 gene variant is linked to open angle glaucoma.

Plain-language title generated from the registry record
Registry title: Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patients in Sohag University Hospital

Key facts

Where
Sohag, EgyptSee the site

Where in Egypt

  • Sohag University HosipitalSohag, EgyptNo longer taking part

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Trial details

Who runs it
Sohag University
Trial code
NCT07119905
Record updated
13 August 2025
Original description
The goal of this observational study is to investigate the potential association between MMP-9 gene polymorphism and susceptibility to Primary Open Angle Glaucoma development in Egyptian patients The main question it aims toRead full original descriptionShow less

Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patients in Sohag University Hospital

The goal of this observational study is to investigate the potential association between MMP-9 gene polymorphism and susceptibility to Primary Open Angle Glaucoma development in Egyptian patients The main question it aims to

Inclusion: Men and women older than 30 years; Primary open angle glaucoma as evidenced from characteristic visual field loss and optic disc cupping (POAG group); Healthy subjects matched by age, sex and ethnicity to the POAG patients group (control group).

Exclusion: History of acute angle closure; Exfoliation glaucoma, pigmentary glaucoma.

ClinicalTrials.gov NCT07119905