Comparing Catheter Ablation Approaches for Persistent Atrial Fibrillation
Compares heart rhythm ablation methods in adults with persistent atrial fibrillation.
Plain-language title generated from the registry record
Registry title: Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation
Key facts
- Where
- Shanghai, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07122336, who can take part
Where in China
- Shanghai Chest HospitalShanghai, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Shanghai Chest Hospital
- Trial code
- NCT07122336
- Record updated
- 14 August 2025
- Original description
The design of this study is an intervention, randomized, controlled study and contains three randomized groups：（1）PVI group；（2）PVI+PWI group;（3）PVI+PWI+EGM group.Read full original descriptionShow less
Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation
The design of this study is an intervention, randomized, controlled study and contains three randomized groups：（1）PVI group；（2）PVI+PWI group;（3）PVI+PWI+EGM group.
Inclusion: Age ≥18 years; First-time ablation for persistent atrial fibrillation (PsAF); Persistent AF definition: Sustained episodes lasting ≥7 days but ≤3 years (including episodes requiring pharmacologic or electrical cardioversion after ≥7 days); Symptomatic AF with intolerance to at least one antiarrhythmic drug (AAD); Documented PsAF episode: At least one recorded PsAF episode within the last 2 years prior to enrollment, confirmed by: ECG,Holter monitorin, Loop recorder, Telemetry, Transtelephonic monitoring (TTM),Implantable device; Ability and willingness to provide written informed consent; Compliance with all study follow-up requirements.
Exclusion: No prior attempt/pursuit of cardioversion or sinus rhythm maintenance; Advanced renal or hepatic failure; Severe valvular heart disease or cyanotic congenital heart disease; Long-standing persistent AF: Continuous AF duration >3 years; Paroxysmal AF: Episodes lasting <7 days (or requiring pharmacologic/electrical cardioversion <7 days); Contraindications to systemic anticoagulation; Pregnancy; Hypertrophic cardiomyopathy (HCM).