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Virtual reality headset training for thinking problems after stroke

Tests virtual reality memory and attention exercises in adults with thinking problems after stroke.

Plain-language title generated from the registry record
Registry title: Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment

Key facts

Where
Independencia, ChileSee the site

Where in Chile

  • Hospital Clínico de la Universidad de ChileIndependencia, ChileTaking people

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  2. Are travel costs paid?
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  4. What happens if I want to stop?
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Trial details

Who runs it
University of Chile
Trial code
NCT07125170
Record updated
15 August 2025
Original description
This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy. Participants will use a head-mounted display and interactive software to engage in gamified cognitive exercises that simulate memory, attention, and executive function tasks. The intervention consists of 10 sessions, delivered two to three times per week over a period of approximately four weeks. The study will assess multiple feasibility indicators, including the recruitment rate based on eligibility criteria, the safety and tolerability of VR sessions for participants, and the usability and satisfaction reported by occupational therapists administering the intervention. Additionally, exploratory outcomes include changes in global cognition and specific cognitive domains, as well as self-reported quality of life. Adverse effects related to VR use will be tracked. This pilot study will help inform the design and implementation of future, larger-scale clinical trials.Read full original descriptionShow less

Immersive Virtual Reality in Cognitive Rehabilitation of Patients With Post-Stroke Cognitive Impairment: A Pilot Study at the Department of Physical Medicine and Rehabilitation, Clinical Hospital of the University of Chile

This pilot study aims to evaluate the feasibility of implementing immersive virtual reality (VR) in cognitive rehabilitation for adults with post-stroke cognitive impairment receiving outpatient therapy. Participants will use a head-mounted display and interactive software to engage in gamified cognitive exercises that simulate memory, attention, and executive function tasks. The intervention consists of 10 sessions, delivered two to three times per week over a period of approximately four weeks. The study will assess multiple feasibility indicators, including the recruitment rate based on eligibility criteria, the safety and tolerability of VR sessions for participants, and the usability and satisfaction reported by occupational therapists administering the intervention. Additionally, exploratory outcomes include changes in global cognition and specific cognitive domains, as well as self-reported quality of life. Adverse effects related to VR use will be tracked. This pilot study will help inform the design and implementation of future, larger-scale clinical trials.

Inclusion: Patients over 18 years of age; Patients with a cerebrovascular accident of any etiology with less than 3 months of progression; Patients with mild to moderate cognitive impairment post-stroke (impairment in at least one cognitive domain); MoCA score of less than 24 points; Referred for cognitive rehabilitation at the Occupational Therapy Unit of HCUCH.

Exclusion: Patients with severe psychiatric disorders (presence of psychotic symptoms or derealization); Patients with refractive errors that prevent the use of the headset; Patients with any type of aphasia that prevents the administration of the MoCA test; Patients with severe motor impairments (lack of trunk control or global strength of both upper limbs < M3).

ClinicalTrials.gov NCT07125170