Checking metabolic health in young children with congenital hypothyroidism

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for prepubertal children aged 5 to 12 years with permanent congenital hypothyroidism. It checks their risk of metabolic syndrome.

Age

5 to 12 years

Sex

All sexes

Disease stage

Permanent congenital hypothyroidism. Pubertal stage Tanner 1.

Main reasons for not taking part

• Younger than 5 years
• Pubertal stage Tanner 2-5
• Transient congenital hypothyroidism
• Other types of hypothyroidism

The registry criteria, word for word

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

• Are you between 5 and 12 years old?YesNo

What the trial wants to find out

We propose a multicenter prospective study to define the prevalence and severity score of metabolic syndrome in a prepubertal pediatric cohort with congenital hypothyroidism, compared to a healthy and normal-weight pediatric population. These data will help to define whether hypothyroidism can be considered a risk factor for the metabolic health of the pediatric population. The possible identification of an at-risk metabolic profile will provide useful information to optimize the diagnostic and monitoring pathway for affected children.

The 3 groups in the trial

• Permanent congenital hypothyroidism

  170 patients in prepubertal age.

  Treatment: prospective observational study (clinical, hormonal and auxological data)

• Healthy childrens normal weight

  170 childrens in prepubertal age.

  Treatment: prospective observational study (clinical, hormonal and auxological data)

• Healthy childrens overweight/obese

  170 patients in prepubertal age

  Treatment: prospective observational study (clinical, hormonal and auxological data)