Checks MRI scans for depth of mouth cancer tumors
Compares MRI tumor depth measurements with tissue exams in people with early mouth cancer.
Plain-language title generated from the registry record
Registry title: Primary Tumor Depth of Invasion and Lymph Node Management in Oral Squamous Cell Carcinoma
Key facts
- Where
- Cairo, EgyptSee the site
Where in Egypt
- AL Sayed Galal Hospital Al-Azhar UniversityCairo, EgyptNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Al-Azhar University
- Trial code
- NCT07127614
- Record updated
- 17 August 2025
- Original description
To evaluate the diagnostic accuracy of preoperative MRI in the determination of the primary tumor depth of invasion (DOI) as a predictor factor in neck lymph nodes management in T1T2N0 oral cavity squamous cell carcinomas as compared to the pathological depth of invasionRead full original descriptionShow less
The Relationship Between Primary Tumor Depth of Invasion and Neck Lymph Nodes Management in T1T2N0 Oral Cavity Squamous Cell Carcinomas
To evaluate the diagnostic accuracy of preoperative MRI in the determination of the primary tumor depth of invasion (DOI) as a predictor factor in neck lymph nodes management in T1T2N0 oral cavity squamous cell carcinomas as compared to the pathological depth of invasion
Inclusion: Patients with biopsy-proven oral squamous cell carcinoma with the edition T1or T2 N0 based on TNM staging by the American Joint Cancer Center AJCC 8th edition; The primary tumor has a depth of invasion (DOI) greater than 4 mm; Clinical N0 status confirmed by reasonable parameters includes computed tomography CT, MRI, -Ultrasonography,( US fine needle aspiration in suspected lymph nodes ); The primary tumor must be reliably resected to a clear margin without the need for entry of the neck for reconstruction.
Exclusion: Patient with gross injury to the neck that precludes proper surgical dissection; Patient with previous neck node biopsy or previous neck dissection; Patient with a history of radiotherapy to the neck; Recurrent cases of OCSCC or recurrent node disease; Patient with a medical condition or performance that interferes with the surgical intervention as judged by the specialist physician; Patients with T3T4 OCSCC; Proven or suspected positive neck node; Patient with distant metastasis.