NCT07131241Recruiting
PH-DyPred: A Multimodal Dynamic Risk Prediction Study in Pulmonary Hypertension
Research on Dynamic Risk Prediction for Patients With Pulmonary Hypertension Based on Multimodal Data Fusion: A Prospective Observational Study
Source: ClinicalTrials.gov · Last updated 6 Oct 2026
Brief summary (registry, in English)
Pulmonary hypertension (PH) is a progressive cardiopulmonary disease characterized by elevated pulmonary artery pressure and vascular remodeling, which leads to right heart failure and increased mortality. Despite advances in diagnostics, risk stratification remains limited due to the disease's heterogeneity. This study aims to develop and validate a dynamic risk prediction model for PH by integrating multimodal data-including echocardiography, Cardiac MRI, PET-MR, ECG, biomarkers, and clinical features-using advanced machine learning algorithms. The study will establish a prospective cohort of PH patients to explore predictive markers, stratify prognosis, and provide a scientific basis for early warning and individualized management.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 6 Aug 2025
- Start date
- 27 Jun 2025
- Primary completion date
- 30 Jun 2028
- Lead sponsor
- First Affiliated Hospital of Fujian Medical University
- NCT number
- NCT07131241
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 27 Jun 2025 to the primary completion date, 30 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Major surgery within the past 3 months
Other illness
- Severe hepatic or renal insufficiency
- Malignancy under active treatment
- Severe infection
- Active autoimmune disease
- Severe psychiatric disorder impairing ability to comply with the study protocol
Other
- Pregnant or breastfeeding women
Who the study is looking for
- Adults aged 18 years or older
- Pulmonary artery systolic pressure (PASP) ≥35 mmHg as estimated by echocardiography
- Provided written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Fujian Medical University Coordinator of this site? Confirm its status | Fuzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.