Organ Effects of Exercise-Triggered High Blood Pressure After Aortic Repair
Studies whether exercise-induced high blood pressure affects the heart, arteries and kidneys in adults.
Plain-language title generated from the registry record
Registry title: Target Organ Damage in Patients With Repaired Coarctation of Aorta and Exercise Induced Hypertension
Key facts
- Where
- Ljubljana, SloveniaSee the site
Where in Slovenia
- UMC LjubljanaLjubljana, SloveniaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Medical Centre Ljubljana
- Trial code
- NCT07134621
- Record updated
- 30 April 2026
- Original description
The goal of this observational study is to obtain data on the effect of exercise induced hypertension on target organs in adult patients with repaired coarctation of the aorta. The main questions it aims to answer are:Read full original descriptionShow less
Target Organ Damage in Patients With Repaired Coarctation of Aorta and Exercise Induced Hypertension
The goal of this observational study is to obtain data on the effect of exercise induced hypertension on target organs in adult patients with repaired coarctation of the aorta. The main questions it aims to answer are:
* patients with exercise induced hypertension have signs of hypertensive heart disease? * patients with exercise induced hypertension have increased arterial stiffness? * patients with exercise induced hypertension have signs of hypertensive renal damage? Participants will be invited for an outpatient appointment during which medical history and physical investigation will be performed. They will undergo cardiopulmonary exercise testing during which blood pressure will be measured regularly. Transthoracic echocardiography will also be performed as well as assessment of arterial stiffness by measuring pulse wave velocity. Renal function will be assessed by blood and urine analysis.
Inclusion: adult patients aged 18 years and older; history of coarctation of aorta repair.
Exclusion: antihypertensive therapy; arterial hypertension at rest; associated haemodynamically significant valvular heart disease; associated complex congenital heart disease; advanced heart failure; symptomatic arrhythmias; haemodynamically significant recoarctation; cognitive or physical limitations to perform exercise stress testing.