Organ Effects of Exercise-Triggered High Blood Pressure After Aortic Repair
Studies whether exercise-induced high blood pressure affects the heart, arteries and kidneys in adults.
Key facts
- Who runs it
- University Medical Centre Ljubljana
- Where
- Ljubljana, SloveniaSee the site
- Trial code
- Registry title
- Target Organ Damage in Patients With Repaired Coarctation of Aorta and Exercise Induced Hypertension
- Status
- Enrolling by invitation
- People taking part
- 50 people, planned
- Started
- 16 Jul 2025
- Planned end
- Aug 2026
- Type of study
- Observational
- Record updated
- 30 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who had surgery or repair for coarctation of the aorta (a narrowing of the main body artery). It studies how high blood pressure during exercise affects the heart, arteries and kidneys.
- Age
- 18 years and older
- Sex
- All sexes can join.
- Disease stage
- Adults with a history of repaired coarctation of the aorta.
- Earlier treatment
- Must have had a coarctation of aorta repair. Must not be taking blood pressure medicine.
Main reasons for not taking part
- Significant re-narrowing of the aorta that affects blood flow
- High blood pressure at rest
- Taking blood pressure medicine
- Significant heart valve disease or complex congenital heart disease
- Advanced heart failure, symptomatic arrhythmias, or being unable to do an exercise test
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- adult patients aged 18 years and older
- history of coarctation of aorta repair
Who cannot take part
- antihypertensive therapy
- arterial hypertension at rest
- associated haemodynamically significant valvular heart disease
- associated complex congenital heart disease
- advanced heart failure
- symptomatic arrhythmias
- haemodynamically significant recoarctation
- cognitive or physical limitations to perform exercise stress testing
Where in Slovenia
- UMC LjubljanaLjubljana, SloveniaNo longer taking part
About the trial
What the trial wants to find out
The goal of this observational study is to obtain data on the effect of exercise induced hypertension on target organs in adult patients with repaired coarctation of the aorta. The main questions it aims to answer are:
Read full original descriptionShow less
* patients with exercise induced hypertension have signs of hypertensive heart disease? * patients with exercise induced hypertension have increased arterial stiffness? * patients with exercise induced hypertension have signs of hypertensive renal damage? Participants will be invited for an outpatient appointment during which medical history and physical investigation will be performed. They will undergo cardiopulmonary exercise testing during which blood pressure will be measured regularly. Transthoracic echocardiography will also be performed as well as assessment of arterial stiffness by measuring pulse wave velocity. Renal function will be assessed by blood and urine analysis.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Target Organ Damage in Patients With Repaired Coarctation of Aorta and Exercise Induced Hypertension
- Plain-language title
- Organ Effects of Exercise-Triggered High Blood Pressure After Aortic RepairGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 30 April 2026