Imaging Test for Joint Inflammation in People with Rheumatoid Arthritis
Tests a scan that looks for inflamed joint lining in adults with rheumatoid arthritis.
Plain-language title generated from the registry record
Registry title: Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis
Key facts
- Where
- Beijing, ChinaSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07138729, who can take part
Where in China
- Peking Union Medical College HospitalBeijing, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Luo Yaping
- Trial code
- NCT07138729
- Record updated
- 24 August 2025
- Original description
This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial lesions in RA patients, aiming to validate its diagnostic consistency with both PET/CT and physical examinations while correlating imaging findings with clinical disease activity metrics to establish a practical tool for long-term RA monitoring.Read full original descriptionShow less
Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis
This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial lesions in RA patients, aiming to validate its diagnostic consistency with both PET/CT and physical examinations while correlating imaging findings with clinical disease activity metrics to establish a practical tool for long-term RA monitoring.
Inclusion: Age: 18-75 years old; Meet the classification criteria for rheumatoid arthritis of the American College of Rheumatology/European Union for Rheumatology in 2010; The highest disease activity in clinical practice (CDAI or SDAI score.
Exclusion: Patients with concurrent tumors; Patients with other autoimmune diseases; Active infection; Suffering from claustrophobia or other mental disorders, with poor compliance resulting in inability to cooperate with this researcher; (6) Situations where other researchers consider it inappropriate to participate in this clinical trial; Women who are pregnant or planning to become pregnant, women in the preconception period, pregnant and lactating women, and women with child-rearing plans during the study period; Subjects of childbearing age need to take effective contraceptive measures during the research process.