Surgery of Dystonia
Key facts
- Where
- Sohag, EgyptSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 10 and 70 years old?
Source: NCT07140302, who can take part
Where in Egypt
- Sohag Faculity of MedicineSohag, EgyptContact: ahmrd mahmoud mostafa, assistant lecturerNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Sohag University
- Trial code
- NCT07140302
- Record updated
- 24 August 2025
- Original description
The goal of this clinical trial is to evaluate the safety and clinical outcomes of stereotactic surgery (Deep Brain Stimulation or Radiofrequency Lesioning) in patients with dystonia.Read full original descriptionShow less
Stereotactic Surgical Management of Dystonia: Efficacy and Safety
The goal of this clinical trial is to evaluate the safety and clinical outcomes of stereotactic surgery (Deep Brain Stimulation or Radiofrequency Lesioning) in patients with dystonia.
The main questions it aims to answer are:
* Does stereotactic surgery improve dystonia severity as measured by the Burke-Fahn-Marsden Dystonia Rating Scale - Motor (BFMDRS-M)? * Are the procedures safe, with an acceptable complication profile during follow-up?
Participants will:
* Undergo stereotactic surgery for dystonia (either Deep Brain Stimulation or Radiofrequency Lesioning, based on clinical indication). * Be followed postoperatively for assessment of motor function and adverse events at the first postoperative week and six months after surgery.
Inclusion: Diagnosed with dystonia with at least 1-year duration since symptom onset; Inadequate relief of dystonia following treatment with standard pharmacotherapies (e.g., levodopa, clonazepam, trihexyphenidyl, or baclofen) or botulinum toxin injections.
Exclusion: Previous DBS surgery; Underwent DBS combined with another surgical procedure for dystonia (e.g., lesioning or peripheral denervation); Cognitive dysfunction or other neuropsychiatric disorders; Progressive neurological conditions other than dystonia; Coagulopathy or bleeding disorders.