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Tests an ear stimulation device for long-lasting pain after stroke

Tests at-home ear stimulation for chronic pain in adults after a stroke.

Plain-language title generated from the registry record
Registry title: Post-stroke Pain tAN-fMRI

Key facts

Where
Charleston, United StatesSee the 2 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT07144436, who can take part

Where in United States

  • 30 Bee StreetCharleston, United StatesTaking people
  • Medical University of South CaroliaCharleston, United StatesNot yet recruiting

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Medical University of South Carolina
Trial code
NCT07144436
Record updated
11 September 2026
Original description
The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke. Investigators will recruit up to 24 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.Read full original descriptionShow less

Investigating the Feasibility, Efficacy, and Renormalization of Pain-Regulation Brain Circuits Underlying At-Home Transcutaneous Auricular Neuromodulation (tAN) for Managing Chronic Post-Stroke Pain

The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke. Investigators will recruit up to 24 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.

Inclusion: Age 18-80; Have the capacity and ability to provide one's own consent in English and sign the informed consent document; Ischemic or hemorrhagic stroke that occurred at least 6 months prior.

Exclusion: Primary intracerebral hematoma or subarachnoid hemorrhage; Documented history of dementia; Documented history of uncontrolled depression or psychiatric disorder; Uncontrolled hypertension despite treatment, specifically SBP (Systolic Blood Pressure) / DBP (Diastolic Blood Pressure) >=180/100mmHg; Contraindicated for MRI scanning; Pregnancy.

ClinicalTrials.gov NCT07144436