Tests personalized biologic selection for psoriasis and psoriatic arthritis
Compares a prescreen-guided versus standard approach to choosing biologic treatment in adults with psoriasis.
Plain-language title generated from the registry record
Registry title: A Multi-center RCT Clinical Trial on Personalized Precision Medicine for Patients With Psoriasis and Psoriatic Arthritis and Investigation on Cardiovascular Biomarkers
Key facts
- Where
- Taichung, TaiwanSee the 2 sites
- Phase
- Phase 4
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 75 with psoriasis or psoriatic arthritis, and also healthy volunteers, who agree to give a blood sample.
- Age
- 18 to 75 years
- Sex
- All sexes can join.
- Disease stage
- Psoriasis confirmed by a dermatologist, or psoriatic arthritis confirmed by a rheumatologist.
Main reasons for not taking part
- Current history of cancer
- Recent hospitalization for infection
- Current antibiotic treatment
- HIV infection
- Active infection or suspected cancer
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT07149792, who can take part
Where in Taiwan
- Taichung Vertenans General HospitalTaichung, TaiwanContact: James Yen, PhDTaking people
- Taichung Veterans HospitalTaichung, TaiwanContact: James Yen, MD PhDNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Taichung Veterans General Hospital
- Trial code
- NCT07149792
- Record updated
- 2 September 2025
- Original description
The inclusion criteria for this study were patients aged 18 to 75 years with a confirmed diagnosis of psoriasis by a dermatologist or psoriatic arthritis by a rheumatologist. Patients with active infections or suspected malignancies were excluded.Read full original descriptionShow less
A Multi-center RCT Clinical Trial on Personalized Precision Medicine for Patients With Psoriasis and Psoriatic Arthritis and Investigation on Cardiovascular Biomarkers
The inclusion criteria for this study were patients aged 18 to 75 years with a confirmed diagnosis of psoriasis by a dermatologist or psoriatic arthritis by a rheumatologist. Patients with active infections or suspected malignancies were excluded.
A total of 40 patients with psoriasis, with or without psoriatic arthritis, were enrolled from multiple centers in Taiwan. All participants were recruited from the outpatient clinics of either the Department of Allergy, Immunology, and Rheumatology or the Department of Dermatology in tertiary hospitals across Taiwan.
Participants were randomly assigned to one of two groups:
Prescreen Strategy-Based Biologics Selection Group
Standard-Based Biologics Selection Group
Patients will be followed up at weeks 4, 8, 12, 24, 32, 40, 48, 56, 64, and 72. Follow-up may be extended up to 3 years if necessary.
Clinical assessments will include:
Primary endpoints: PASI (Psoriasis Area and Severity Index), painful joint count, swollen joint count, and DAPSA (Disease Activity in Psoriatic Arthritis) score.
Secondary endpoints: DLQI (Dermatology Life Quality Index), BSA (Body Surface Area), pruritus score, and internal carotid artery thickness measured at 6 months, 1 year, and 2 years.
Inclusion: Healthy subjects; Psoriasis patients; Psoriatic arthritis patients; Agree to provide a blood sample.
Exclusion: A current history of cancer,; Recent hospitalization for infection or current antibiotic treatment; HIV infection.