Tests brain stimulation to help arm recovery after stroke
Tests mild electrical brain stimulation against a sham in stroke patients with weak arms.
Plain-language title generated from the registry record
Registry title: Use of Anodal tDCS to Enhance Upper Limb Recovery in Stroke
Key facts
- Where
- Singapore, SingaporeSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 80 years old?
Source: NCT07151729, who can take part
Where in Singapore
- Tan Tock Seng Hospital - Integrated Care HubSingapore, SingaporeTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Tan Tock Seng Hospital
- Trial code
- NCT07151729
- Record updated
- 3 September 2025
- Original description
This will be a randomized, blinded, sham-controlled trial. The medical device used, Soterix Medical 1x1 tDCS stimulator, is capable of delivering either real or sham tDCS and has been used in many randomised controlled trials in stroke patients.Read full original descriptionShow less
Use of Anodal Transcranial Direct Current Stimulation to Enhance Upper Limb Recovery in Stroke
This will be a randomized, blinded, sham-controlled trial. The medical device used, Soterix Medical 1x1 tDCS stimulator, is capable of delivering either real or sham tDCS and has been used in many randomised controlled trials in stroke patients.
50 patients with subacute stroke and severe upper limb weakness within 8 weeks of stroke on transfer to TTSH stroke rehab wards will be recruited over a period of 10 months. Recruited patients will be randomized into the intervention and control arms in a 1:1 ratio.
Inclusion: First ever unilateral ischaemic or haemorrhagic stroke, as documented by CT or MRI scans; Age 21-80 years, both males and females; Within 8 weeks of stroke onset; Severe weakness of one upper limb, defined by a Shoulder Abduction and Finger Extension (SAFE) score < 5 (Medical Research Council grading); Provision of informed consent by patient or a legal guardian in accordance with the local ethics committee guidelines and the Declaration of Helsinki.
Exclusion: Presence of brain implants, and previous insertion of external ventricular drains; Metallic implants at the level of the neck, mouth cavity and below are permitted (e.g. Cardiac stents, dental implants, pacemakers and other metallic objects); A history of spontaneous seizures, epilepsy, brain tumour, and cranial surgery; Severe cognitive impairment (MOCA Score <10) that would hinder sufficient understanding of the instructions; Bilateral hemispheric or cerebellar strokes; Pre-existing arm pathology (e.g. contracture, severe pain, etc.) on the affected side; Pregnancy.