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NCT07152977Completed

Description of the Radiological Response of Anoperineal Fistulizing Lesions of Crohn's Disease

Description of the Radiological Response of Anoperineal Fistulizing Lesions of Crohn's Disease in Patients Treated With Biotherapy

Source: ClinicalTrials.gov · Last updated 3 Sept 2025

Brief summary (registry, in English)

The presence of ano-perineal lesions (APL) in Crohn's disease is common and represents a major burden for the patient. More than one-third of patients with Crohn's disease will develop at least one ano-perineal lesion during the course of their disease. The cumulative incidence of APL is approximately 30% at 10 years and 43% at 20 years, regardless of the type of APL. The appearance of ano-perineal lesions represents an important phase in the progression of Crohn's disease, but they have been little studied to date. There is little consensus regarding their overall management. Indeed, their management is difficult due to their destructive and recurrent nature, and their significant impact on patients' quality of life, continence, and sexuality is significant. The presence of ano-perineal lesions at the time of diagnosis, especially in young patients, is a poor prognostic factor.

Status (registry)
Completed
Study type
Observational
Enrollment
52 (actual)
First submitted
25 Aug 2025
Start date
31 Jul 2019
Primary completion date
31 Jan 2024
Lead sponsor
University Hospital, Rouen
NCT number
NCT07152977

What you commit to

  • Study type: Observational
  • Participants enrolled: 52
  • From 31 Jul 2019 to the primary completion date, 31 Jan 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients who have received surgical treatment with a stoma for perineal disease

Other illness

  • Patients with an anoperineal lesion, without Crohn's disease

Other

  • Minor patients

Who the study is looking for

  • All adult patients, monitored at the Rouen University Hospital for Crohn's disease, complicated by fistulizing anoperineal lesion, treated with Biotherapy, having benefited from an MRI at the start of treatment and during follow-up.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Rouen Hospital
Coordinator of this site? Confirm its status
RouenFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.