NCT07152977Completed
Description of the Radiological Response of Anoperineal Fistulizing Lesions of Crohn's Disease
Description of the Radiological Response of Anoperineal Fistulizing Lesions of Crohn's Disease in Patients Treated With Biotherapy
Source: ClinicalTrials.gov · Last updated 3 Sept 2025
Brief summary (registry, in English)
The presence of ano-perineal lesions (APL) in Crohn's disease is common and represents a major burden for the patient. More than one-third of patients with Crohn's disease will develop at least one ano-perineal lesion during the course of their disease. The cumulative incidence of APL is approximately 30% at 10 years and 43% at 20 years, regardless of the type of APL. The appearance of ano-perineal lesions represents an important phase in the progression of Crohn's disease, but they have been little studied to date. There is little consensus regarding their overall management. Indeed, their management is difficult due to their destructive and recurrent nature, and their significant impact on patients' quality of life, continence, and sexuality is significant. The presence of ano-perineal lesions at the time of diagnosis, especially in young patients, is a poor prognostic factor.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 52 (actual)
- First submitted
- 25 Aug 2025
- Start date
- 31 Jul 2019
- Primary completion date
- 31 Jan 2024
- Lead sponsor
- University Hospital, Rouen
- Diseases
- Crohn's disease
- NCT number
- NCT07152977
What you commit to
- Study type: Observational
- Participants enrolled: 52
- From 31 Jul 2019 to the primary completion date, 31 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who have received surgical treatment with a stoma for perineal disease
Other illness
- Patients with an anoperineal lesion, without Crohn's disease
Other
- Minor patients
Who the study is looking for
- All adult patients, monitored at the Rouen University Hospital for Crohn's disease, complicated by fistulizing anoperineal lesion, treated with Biotherapy, having benefited from an MRI at the start of treatment and during follow-up.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Rouen Hospital Coordinator of this site? Confirm its status | Rouen | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.