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AI Imaging Tool to Tell Inflammatory From Degenerative Joint Disease in Older Adults

Tests AI image analysis to tell two kinds of joint disease apart.

Plain-language title generated from the registry record
Registry title: AI-Based Medical Data Analysis for Differentiating Inflammatory vs Degenerative Joint Diseases in Elderly Patients

Key facts

Where
Asyut, EgyptSee the site

Where in Egypt

  • Assiut University hospitalAsyut, EgyptNo longer taking part

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Trial details

Who runs it
Assiut University
Trial code
NCT07153315
Record updated
3 September 2025
Original description
This study aims to evaluate the diagnostic accuracy of AI-assisted imaging analysis in differentiating between inflammatory and degenerative joint diseases in elderly patients. The performance of AI-based analysis will be compared with radiologists' assessments to determine its reliability in clinical practice. In addition, the study will explore imaging features most predictive of each disease type using advanced machine learning techniques. Finally, the feasibility of implementing AI tools in the routine management of geriatric musculoskeletal disorders will be assessed.Read full original descriptionShow less

Artificial Intelligence-Enhanced Medical Data Analysis for Differentiating Inflammatory and Degenerative Joint Diseases and Detecting of Disease Severity in Elderly Patient

This study aims to evaluate the diagnostic accuracy of AI-assisted imaging analysis in differentiating between inflammatory and degenerative joint diseases in elderly patients. The performance of AI-based analysis will be compared with radiologists' assessments to determine its reliability in clinical practice. In addition, the study will explore imaging features most predictive of each disease type using advanced machine learning techniques. Finally, the feasibility of implementing AI tools in the routine management of geriatric musculoskeletal disorders will be assessed.

Inclusion: Age ≥ 60 years; Clinical suspicion or confirmed diagnosis of inflammatory joint disease (e.g., rheumatoid arthritis, psoriatic arthritis) or degenerative joint disease (e.g., osteoarthritis); Availability of relevant musculoskeletal imaging (X-rays, MRI, or ultrasound) suitable for AI-based analysis; Ability to provide informed consent or have a legal representative consent on behalf of the.

Exclusion: History of recent joint trauma (within the last 6 months) or previous joint surgery affecting the studied sites; Diagnosis of overlapping rheumatologic syndromes or mixed pathology (e.g., RA with concurrent gout, or OA with inflammatory overlap); Presence of bone or joint malignancy (primary or metastatic); Inadequate imaging quality or absence of required imaging modalities; Inability or unwillingness to provide informedconsent.

ClinicalTrials.gov NCT07153315