Tests brain stimulation for swallowing trouble in Parkinson's disease
Tests mild brain stimulation with usual swallowing therapy in Parkinson's patients.
Plain-language title generated from the registry record
Registry title: Clinical Efficacy and Mechanism of tDCS for Dysphagia in PD
Key facts
- Where
- Hangzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with Parkinson's disease who have swallowing problems. It tests brain stimulation (tDCS) together with usual swallowing treatment.
- Age
- 18 to 100 years
- Sex
- All sexes can join.
- Disease stage
- Parkinson's disease, or multiple system atrophy or progressive supranuclear palsy, with swallowing problems shown on a VFSS swallowing X-ray test.
- Biomarker or test result
- Mini-Mental State Examination (MMSE) score above 23.
Main reasons for not taking part
- Another disease that causes swallowing problems
- Pneumonia
- Severe heart or kidney failure
- Metal implants in the body
- Memory or thinking problems, or unable to cooperate
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 100 years old?
Source: NCT07153692, who can take part
Where in China
- Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou, ChinaContact: Ping Wang, MSTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Wang Ping
- Trial code
- NCT07153692
- Record updated
- 4 September 2025
- Original description
This study aims to verify transcranial direct current stimulation(tDCS) efficacy for Parkinson's disease (PD)-related dysphagia and its mechanism. Subjects are randomly split into two groups: control (sham tDCS + conventional dysphagia treatment) and experimental (real tDCS + conventional treatment).Read full original descriptionShow less
Clinical Efficacy and Mechanism of tDCS for Dysphagia in Patients With Parkinson's Disease
This study aims to verify transcranial direct current stimulation(tDCS) efficacy for Parkinson's disease (PD)-related dysphagia and its mechanism. Subjects are randomly split into two groups: control (sham tDCS + conventional dysphagia treatment) and experimental (real tDCS + conventional treatment).
Assessments will be conducted at baseline, after the completion of intervention, and at the 3-month follow-up. Swallowing function will be evaluated via gold-standard videofluoroscopic swallowing study (VFSS) and scales. Resting-state functional magnetic resonance imaging (rs-fMRI) or functional near-infrared spectroscopy (fNIRS) will be measures for tracking changes in abnormal brain regions/networks.
Correlations between swallowing recovery and brain function changes, plus group imaging differences, will reveal tDCS's neurophysiological mechanism.
Inclusion: Meet the Chinese Diagnostic Criteria for Parkinson's Disease (2016) or MDS Diagnostic Criteria for Multiple System Atrophy or Progressive Supranuclear Palsy; VFSS examination indicates dysphagia; Mini-Mental State Examination (MMSE) score >23; Willing to cooperate with the study and sign the informed consent form.
Exclusion: Having metal implants in the body; Comorbid with other diseases that cause dysphagia; Comorbid with pneumonia, or severe cardiac/renal insufficiency; With cognitive impairment or inability to cooperate.