Checking how accurately a room-sized device measures energy burned
Tests whether a whole-room calorimeter estimates energy balance in healthy adults.
Plain-language title generated from the registry record
Registry title: Validation of Energy Expenditure Measures Study
Key facts
- Where
- Leipzig, GermanySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07155564, who can take part
Where in Germany
- Department of Internal Medicine, Clinic for Endocrinology, Nephrology and Rheumatology, University of LeipzigLeipzig, GermanyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Leipzig
- Trial code
- NCT07155564
- Record updated
- 14 September 2026
- Original description
The energy that the human body burns and the amount of food consumed determine a person's body weight. If food intake covers the amount of energy burned, body weight remains constant - a state known as energy balance. Achieving an energy balance is not easy in everyday life. This is reflected in the increasing number of people suffering from morbid obesity. To counteract this development, it is important to have a better understanding of how much food a person should eat.Read full original descriptionShow less
Energy Balance Within a Whole-Room Indirect Calorimeter and Its Relevance for Energy Expenditure Measures
The energy that the human body burns and the amount of food consumed determine a person's body weight. If food intake covers the amount of energy burned, body weight remains constant - a state known as energy balance. Achieving an energy balance is not easy in everyday life. This is reflected in the increasing number of people suffering from morbid obesity. To counteract this development, it is important to have a better understanding of how much food a person should eat.
In this study, the investigators will investigate the amount of food needed to meet a person's energy needs and bring them into energy balance.
Primary aims of the study are i) to technically and biologically validate two whole-room indirect calorimeters (WRICs) and ii) by using whole-room indirect calorimetry, to achieve a more accurate estimate of a person's emergy balance compared to common approximation formulas.
Secondary study aims:
1. To investigate whether the transfer of a person into energy balance using WRIC has an influence on energy expenditure measures compared to the transfer into energy balance using the usual approximation formula. 2. To investigate whether the transfer of a person into energy balance using WRIC has an influence on activity-dependent energy expenditure measures compared to the transfer into energy balance using the usual approximation formula. 3. To investigate whether differences in energy expenditure during energy balance during moderate and strenuous physical activity influence food intake. 4. To investigate whether energy intake in relation to energy expenditure during energy balance is related to weight development
Inclusion: Abilty to provide informed consent; Written declaration of consent; Healthy study participants; Able to perform moderate physical exercise using a bike ergometer; Women: continuous contraception/fullicular phase of menstrual cycle.
Exclusion: Nicotine abuse, Alcohol/drug abuse; Chronic diseases with an impact on energy expenditure; Food allergy/intolerance, vegan diet; Circumstances that speak against the application of wearable accelerometers (e.g. silicone contact allergy); Impaired fasting glucose, diabetes mellitus and prediabetes; Weight change > 5 kg or 5% of body weight in the last 3 months; Strenuous physical activity in everyday life > 1 h per day; Body mass index < 18.5 kg/m² or ≥ 40 kg/m²; Pregnancy/breastfeeding; Claustrophobia; Refusal to communicate incidental findings.