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AI Toothbrush Tested for Oral Hygiene in Children With Autism

Tests an AI-enabled electric toothbrush against manual brushing in children with autism.

Key facts

Who runs it
University of Sao Paulo
Where
Ribeirão Preto, BrazilSee the site
Trial code
Registry title
AI Toothbrush and Visual Pedagogy to Improve Oral Hygiene in Children With Autism Spectrum Disorder
Status
Not yet recruiting
People taking part
50 people, planned
Started
1 Oct 2025
Expected to end
10 Feb 2027
Type of study
Interventional, 2 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Visual Pedagogy and Manual Toothbrushing
Record updated
8 September 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for children aged 5-13 with a diagnosis of autism spectrum disorder who are cared for by a caregiver able to use a smartphone or computer.

Age
5 to 13 years
Sex
All sexes
Disease stage
Autism spectrum disorder level 1, 2 or 3, confirmed by a neuropediatrician.

Main reasons for not taking part

  • Severe medical conditions that make dental check-ups unsafe
  • Advanced gum disease or other mouth problems needing urgent dental treatment
  • Caregiver unable or unwilling to use a smartphone, tablet or computer
  • Families who decline to take part at any stage

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Child must be accompanied by a primary caregiver (≥18 years old) responsible for daily oral hygiene
  • Caregiver must have access to a smartphone or computer to interact with the digital platform
  • Written informed consent (TCLE) from the caregiver and assent (TALE) from the child
  • -

Who cannot take part

  • Children with advanced periodontal disease or other oral conditions requiring urgent dental treatment
  • Caregivers who are unable or unwilling to use basic digital platforms (smartphone, tablet, or computer)
  • Families who decline participation at any stage of the study
  • -

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 5 and 13 years old?

Where in Brazil

  • School of Dentistry of Ribeirão Preto - University of São Paulo (FORP-USP)Ribeirão Preto, BrazilContact: Andiara De Rossi, DDS, PhDNo longer taking part

About the trial

What the trial wants to find out

This randomized clinical trial evaluates the effectiveness of an AI-enabled electric toothbrush and visual pedagogy materials in improving oral hygiene among children with autism spectrum disorder (ASD). The study compares plaque control, gingival health, and adherence between children using a manual toothbrush with visual pedagogy support and those using an AI-enabled electric toothbrush with app-based monitoring.

The 2 groups in the trial

  • Manual Toothbrushing + Visual PedagogyExisting treatment, for comparison

    Participants will use a manual toothbrush with caregiver support. Visual pedagogy materials will be provided, including printed picture exchange communication system (PECS) cards illustrating each step of toothbrushing and tactile sensory panels simulating toothbrush bristles, toothpaste texture, and dental floss. Caregivers will be instructed to use these materials daily to improve comprehension and adherence to toothbrushing routines.

    Treatment: Visual Pedagogy and Manual Toothbrushing

  • AI-enabled Electric ToothbrushTreatment being tested

    Participants will use an Oral-B Genius X electric toothbrush equipped with artificial intelligence and Bluetooth connectivity. The device monitors brushing time, sequence, and pressure, providing real-time feedback through a smartphone application. Caregivers will be trained to supervise and encourage daily use at home for 3 weeks. The intervention aims to improve plaque removal and promote autonomy and motivation during oral hygiene in children with ASD.

    Treatment: Visual Pedagogy and Manual Toothbrushing

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Effectiveness of an Artificial Intelligence-Enabled Electric Toothbrush and Visual Pedagogy Materials on Oral Hygiene of Children With Autism Spectrum Disorder
Plain-language title
AI Toothbrush Tested for Oral Hygiene in Children With AutismGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Fit questions
Built from NCT07160517, who can take part
Record updated
8 September 2025