Leg Position Versus Noradrenaline for Blood Pressure During Bypass Surgery
Compares leg-raising positioning with noradrenaline to manage blood pressure in adults having bypass surgery.
Plain-language title generated from the registry record
Registry title: Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery
Key facts
- Where
- Caluire-et-Cuire, FranceSee the site
Where in France
- Infirmerie Protestante de LyonCaluire-et-Cuire, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Infirmerie Protestante de Lyon
- Trial code
- NCT07163858
- Record updated
- 4 November 2026
- Original description
This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.Read full original descriptionShow less
Comparison of Hemodynamic Management by Postural Mobilization Versus Chemical Vasoconstriction Using Noradrenaline Exclusively in Off-pump Coronary Artery Bypass Graft Surgery: A Prospective, Randomized, Comparative, Single-center Study.
This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.
Inclusion: Adult patient; patient requiring isolated coronary bypass surgery; Elective procedure or medical emergency; First cardiac surgery; Patient with an EF ≥30%; Mandatory affiliation to a social security system; Signed informed consent form; Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure.
Exclusion: History of cardiac surgery; Renal failure (GFR < 40 ml/min/1.73 m²); Contraindication to an inotropic substance (only NA will be used); Contraindication to passive leg raising; Patient in a life-threatening emergency; Bilateral iliac or common femoral artery occlusion; EF < 30%; Pregnancy and breastfeeding; Patient with bilateral thigh amputation; Class III obesity BMI > 40 kg/m².