Ultrasound study of blood flow in the gut in systemic sclerosis
Uses Doppler ultrasound to examine blood vessels in the gut of adults with systemic sclerosis.
Plain-language title generated from the registry record
Registry title: Assessment of GIT Vasculopathy in SSc and Its Multisystem Correlations
Key facts
- Where
- Asyut, EgyptSee the site
Where in Egypt
- Assiut University, Assiut, 71111Asyut, EgyptNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Esraa Moustafa Mohammed
- Trial code
- NCT07171437
- Record updated
- 12 September 2025
- Original description
* Evaluation of splanchnic vasculature, including arterial blood flow using Doppler ultrasound in patients with systemic sclerosis compared to healthy subjects. * Correlation of Doppler findings of splanchnic vessels with GIT manifestations. * Correlation of Doppler findings of splanchnic vessels with macrovascular affection (chest, cardiac, and renal), microvascular involvement (capillaroscopy findings), and autoantibodies (anti-SCL70 antibody and anti-centromere antibody).Read full original descriptionShow less
Assessment of Gastrointestinal Vasculopathy in Systemic Sclerosis and Its Multisystem Correlations
* Evaluation of splanchnic vasculature, including arterial blood flow using Doppler ultrasound in patients with systemic sclerosis compared to healthy subjects. * Correlation of Doppler findings of splanchnic vessels with GIT manifestations. * Correlation of Doppler findings of splanchnic vessels with macrovascular affection (chest, cardiac, and renal), microvascular involvement (capillaroscopy findings), and autoantibodies (anti-SCL70 antibody and anti-centromere antibody).
Inclusion: Adult patients aged 18 years or older; Patients classified as systemic sclerosis (SSc) according to ACR/EULAR 2013 classification criteria; Patients who consented to undergo Doppler ultrasound (DUS) assessment of the splanchnic vessels.
Exclusion: Patients with overlapping autoimmune diseases (e.g., lupus, rheumatoid arthritis); Patients with known gastrointestinal disorders not related to systemic sclerosis (e.g., inflammatory bowel disease, celiac disease); Patients with a history of major gastrointestinal surgery (e.g., bowel resection); Patients with diabetes mellitus (due to its independent effects on vascular flow); Presence of severe comorbidities (e.g., end-stage renal disease, decompensated heart failure); Patients younger than 18 years old; Pregnancy or lactation.