Tests how insulin dose timing at meals affects fat storage in type 1 diabetes
Compares meal insulin timing, including skipped doses, in adults with type 1 diabetes.
Plain-language title generated from the registry record
Registry title: The TiMeD-T1D Project
Key facts
- Where
- Aarhus, DenmarkSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 65 with type 1 diabetes. It studies how the timing of meal insulin doses affects fat storage after a meal.
- Age
- 18 to 65 years
- Sex
- All sexes can join.
- Disease stage
- Type 1 diabetes for more than 3 years, or a negative c-peptide test.
- Biomarker or test result
- Either diabetes duration over 3 years or a c-peptide negative result.
Main reasons for not taking part
- Taking medicine that affects blood sugar or blood pressure
- BMI above 35 kg/m2 or below 18.5 kg/m2
- Alcohol or substance abuse
- Lactose intolerance
- Does not speak and understand Danish
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07172672, who can take part
Where in Denmark
- Department of Nuclear Medicine & PET-Centre, AUH Palle Juul-Jensens Blvd. 165, 8200 Aarhus N, Denmark and Medical Research Laboratories/Steno Diabetes Center Aarhus, AUH Palle Juul-Jensens Blvd. 11, 8200 Aarhus N, DenmarkAarhus, DenmarkNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Aarhus
- Trial code
- NCT07172672
- Record updated
- 26 September 2025
- Original description
The aim of the proposed study is to investigate the metabolic consequences of varying the timing of meal insulin boluses and skipping boluses altogether in individuals with type 1 diabetes.Read full original descriptionShow less
Impact of Meal Insulin Dose Timing on Meal Fat Storage in Patients With Type 1 Diabetes: a Randomized Control Trial - the TiMeD-T1D Project
The aim of the proposed study is to investigate the metabolic consequences of varying the timing of meal insulin boluses and skipping boluses altogether in individuals with type 1 diabetes.
The investigator hypothesize that delaying or skipping meal insulin boluses leads to greater ectopic fat storage due to a delayed stimulation of lipoprotein activity and delayed suppression of lipolysis and VLDL-TG secretion.
Inclusion: Type 1 diabetes duration > 3 years or c-peptide negative; Written and informed consent.
Exclusion: Participation in other clinical trials involving ionized radiation within the last 6 months; Medicine with an impact on blood glucose or blood pressure; Affected screening blood sample as evaluated by the clinical responsible investigator; Alcohol or substance abuse; BMI > 35 kg/m2 or < 18.5 kg/m2; Lactose intolerance; Doesn't speak and understand Danish; Severe claustrophobia; Commitment to special diets.