Tests how insulin dose timing at meals affects fat storage in type 1 diabetes
Compares meal insulin timing, including skipped doses, in adults with type 1 diabetes.
Plain-language title generated from the registry record
Registry title: The TiMeD-T1D Project
Key facts
- Where
- Aarhus, DenmarkSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07172672, who can take part
Where in Denmark
- Department of Nuclear Medicine & PET-Centre, AUH Palle Juul-Jensens Blvd. 165, 8200 Aarhus N, Denmark and Medical Research Laboratories/Steno Diabetes Center Aarhus, AUH Palle Juul-Jensens Blvd. 11, 8200 Aarhus N, DenmarkAarhus, DenmarkNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Aarhus
- Trial code
- NCT07172672
- Record updated
- 26 September 2025
- Original description
The aim of the proposed study is to investigate the metabolic consequences of varying the timing of meal insulin boluses and skipping boluses altogether in individuals with type 1 diabetes.Read full original descriptionShow less
Impact of Meal Insulin Dose Timing on Meal Fat Storage in Patients With Type 1 Diabetes: a Randomized Control Trial - the TiMeD-T1D Project
The aim of the proposed study is to investigate the metabolic consequences of varying the timing of meal insulin boluses and skipping boluses altogether in individuals with type 1 diabetes.
The investigator hypothesize that delaying or skipping meal insulin boluses leads to greater ectopic fat storage due to a delayed stimulation of lipoprotein activity and delayed suppression of lipolysis and VLDL-TG secretion.
Inclusion: Type 1 diabetes duration > 3 years or c-peptide negative; Written and informed consent.
Exclusion: Participation in other clinical trials involving ionized radiation within the last 6 months; Medicine with an impact on blood glucose or blood pressure; Affected screening blood sample as evaluated by the clinical responsible investigator; Alcohol or substance abuse; BMI > 35 kg/m2 or < 18.5 kg/m2; Lactose intolerance; Doesn't speak and understand Danish; Severe claustrophobia; Commitment to special diets.