Looks for markers in fluid and tissue of women with endometriosis
Studies biological markers in uterine fluid and tissue of women with endometriosis.
Plain-language title generated from the registry record
Registry title: Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate/Severe Endometriosis Patients
Key facts
- Where
- Stockholm, SwedenSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 40 years old?
Source: NCT07182643, who can take part
Where in Sweden
- Karolinska Institute and Karolinska University Hospital HuddingeStockholm, SwedenNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Region Stockholm
- Trial code
- NCT07182643
- Record updated
- 19 September 2025
- Original description
This study aims to explore biomarkers in the endometrial fluid and tissue of women with moderate to severe endometriosis, with a specific focus on those involved in pre-receptive endometrium and embryo implantation. This research has the potential to uncover diagnostic indicators of impaired pre-receptive endometrium, examine pathophysiological pathways, and identify future targets for therapeutic intervention. Ultimately, the findings may contribute to more personalized fertility treatments, offering new hope for women struggling with endometriosis-related infertility.Read full original descriptionShow less
An Exploratory Study of Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate/Severe Endometriosis Patients: a Prospective Study
This study aims to explore biomarkers in the endometrial fluid and tissue of women with moderate to severe endometriosis, with a specific focus on those involved in pre-receptive endometrium and embryo implantation. This research has the potential to uncover diagnostic indicators of impaired pre-receptive endometrium, examine pathophysiological pathways, and identify future targets for therapeutic intervention. Ultimately, the findings may contribute to more personalized fertility treatments, offering new hope for women struggling with endometriosis-related infertility.
Inclusion: Age 18-40 years old; Diagnosed with moderate/severe endometriosis by ultrasound or laparoscopy (patient group); Regular menstrual cycles 28-35 days; Speak English or Swedish and agree to participate in the study.
Exclusion: Major abdominal or pelvic surgery in the last 3 months; Pelvic inflammatory disease, endometritis, STD; Gynaecological cancers or other malignancies in the patient's history; A specific genetic disease that is diagnosed before PGT in women undergoing treatment; Pregnancy or lactation in the last 3 months; Uterine anomalies; Smoking (more than 10 cigarettes per day) or alcohol abuse; Immunosuppressing medicines.