Testing a gene-guided diet for people with systemic lupus erythematosus
Tests a diet chosen from genetic results in adults with systemic lupus erythematosus.
Plain-language title generated from the registry record
Registry title: Development of a Dietary Intervention Model Based on Genetic Data as an Implementation of a Healthy Lifestyle in the Management of Systemic Lupus Erythematosus Patients
Key facts
- Where
- Jakarta Pusat, IndonesiaSee the site
Where in Indonesia
- Cipto Mangunkusumo HospitalJakarta Pusat, IndonesiaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universitas Indonesia
- Trial code
- NCT07183007
- Record updated
- 19 September 2025
- Original description
The goal of this clinical trial is to learn if dietary intervention based on genetic data benefits in the management of systemic lupus erythematosus patients. It will also learn about the safety of this intervention. The main questions it aims to answer are:Read full original descriptionShow less
Development of a Dietary Intervention Model Based on Genetic Data as an Implementation of a Healthy Lifestyle in the Management of Systemic Lupus Erythematosus Patients
The goal of this clinical trial is to learn if dietary intervention based on genetic data benefits in the management of systemic lupus erythematosus patients. It will also learn about the safety of this intervention. The main questions it aims to answer are:
* What is the effect of dietary intervention based on genetic data as part of a healthy lifestyle in the management of SLE patients on disease activity? * What is the effect of dietary intervention based on genetic data as part of a healthy lifestyle in the management of SLE patients on quality of life Researchers would compare dietary intervention based on genetic data to a no intervention to see if dietary intervention based on genetic data improves disease activity and quality of life of SLE patients.
Participants will:
* Be checked for genetic test (HLA DQ2 and DQ8) as screening * Be randomized to dietary intervention group or control group if has HLA DQ2 or DQ8 positive from screening * Visit the clinic once every month for checkups and lab test if were randomized to dietary intervention group or control group * Do food record as instructed if were randomized to dietary intervention group or control group
Inclusion: Patients with systemic lupus erythematosus (SLE) diagnosed according to the 2019 EULAR/ACR criteria, registered as patients at RSCM; Age above 18 years.
Exclusion: Presence of active infection; Already on a specific autoimmune-related diet; Patients with severe medical conditions (active cancer, stage V chronic kidney disease, or acute heart failure); Patients taking corticosteroids equivalent to more than 20 mg/dL prednisone; Refusal to participate in the study; Pregnancy; Breastfeeding.