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Testing urine DNA to decide how often bladder cancer patients need checkups

Tests a urine tumor DNA test to see who can have fewer bladder checks.

Plain-language title generated from the registry record
Registry title: Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer

Key facts

Where
Burlington, United StatesSee the site

Where in United States

  • Lahey Hospital and Medical CenterBurlington, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Lahey Clinic
Trial code
NCT07187063
Record updated
3 November 2026
Original description
The goal of this clinical trial is to use urine tumor DNA (utDNA) as an indicator for non-muscle invasive bladder cancer to identify patients suitable for less frequent cystoscopy surveillance.Read full original descriptionShow less

Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer

The goal of this clinical trial is to use urine tumor DNA (utDNA) as an indicator for non-muscle invasive bladder cancer to identify patients suitable for less frequent cystoscopy surveillance.

Inclusion: AUA high-risk bladder cancer1; Received induction BCG or gemcitabine/docetaxel; Negative initial post-induction therapy assessment (negative cytology and cystoscopy +/- biopsy).

Exclusion: Prior induction intravesical therapy; Concurrent upper tract disease; High-risk NMIBC within 3 years; Variant histology.

ClinicalTrials.gov NCT07187063