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Ultrasound Methods to Detect Tendon Inflammation in Psoriatic Arthritis

Compares ultrasound methods for spotting tendon inflammation in adults with psoriatic arthritis.

Plain-language title generated from the registry record
Registry title: SWE to Detect Enthesitis in PsA: Relationship With SIRT2 Expression and Disease Activity

Key facts

Where
Asyut, EgyptSee the site

Where in Egypt

  • Assiut UniversityAsyut, EgyptNo longer taking part

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Trial details

Who runs it
Assiut University
Trial code
NCT07188688
Record updated
23 September 2025
Original description
1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis. 2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels. 3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.Read full original descriptionShow less

Shear-Wave Elastography to Detect Enthesitis in Psoriatic Arthritis: Relationship With SIRT2 Expression and Disease Activity

1. To assess the diagnostic utility of shear-wave elastography (SWE), gray-scale (GS) ultrasound, and Power Doppler (PD) in detecting Patellar and Achilles tendinopathy in psoriatic patients with and without arthritis. 2. Investigate the relation between SWE, GS ultrasound, and PD finding and SIRT2 expression levels. 3. Evaluate the association of the imaging findings and SIRT2 levels with psoriatic arthritis disease activity score.

Inclusion: Patients diagnosed as PsO by a dermatologist according to PASI score; Patients diagnosed as PsA by rheumatologist according to CASPAR classification criteria for psoriatic arthritis; Adult patients of both sexes with an average > 18 years.

Exclusion: Patients with a history of metabolic disease affecting tendons; Patients with history of surgery, injury or trauma of patellar and/or Achilles tendon; Patients with other rheumatological diseases; Patients below 18.

ClinicalTrials.gov NCT07188688