Balloon Guide Catheter Test for Stroke Clot Removal in Carotid Artery Blockages
Tests a balloon catheter during clot removal in adults with stroke.
Plain-language title generated from the registry record
Registry title: Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery
Key facts
- Where
- Beijing, Fuzhou, and Zhangzhou, ChinaSee the 3 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults having a sudden stroke caused by a blocked internal carotid artery, who are going to have a clot-removal procedure (thrombectomy).
- Age
- 18 years or older
- Sex
- All sexes
- Disease stage
- Acute ischemic stroke with internal carotid artery blockage confirmed by imaging; NIHSS score of 6 or more; within 24 hours of onset or last known normal.
Main reasons for not taking part
- Bleeding in the brain on imaging
- Blockage known or suspected to be caused by dissection or atherosclerosis
- Pre-stroke mRS score above 2
- Pregnancy
- Expected lifetime of less than 90 days
Read by machine on 12 November 2026.
Where in China
- Xuanwu Hospital, Capital Medical UniversityBeijing, ChinaContact: Liqun Jiao, Dr.Taking people
- Fujian Medical University Union HospitalFuzhou, ChinaContact: Wenhuo Chen, Dr.Taking people
- Zhangzhou Municipal HospitalZhangzhou, ChinaContact: Tingyu Yi, Dr.Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Xuanwu Hospital, Beijing
- Trial code
- NCT07192029
- Record updated
- 17 November 2025
- Original description
To investigate whether using balloon guide catheter with flow arrest during mechanical thrombectomy, compared to non-flow arrest, improves the rate of first pass expanded Thrombolysis in Cerebral Infarction score (eTICI 2c-3) reperfusion for acute ischemic stroke due to internal carotid artery occlusionRead full original descriptionShow less
Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery: a Randomized Controlled Trial
To investigate whether using balloon guide catheter with flow arrest during mechanical thrombectomy, compared to non-flow arrest, improves the rate of first pass expanded Thrombolysis in Cerebral Infarction score (eTICI 2c-3) reperfusion for acute ischemic stroke due to internal carotid artery occlusion
Inclusion: age ≥18 years; Clinical diagnosis of acute ischemic stroke with internal carotid artery occlusion confirmed by imaging (CTA/MRA/DSA), including isolated intracranial internal carotid artery (I-type), internal carotid artery intracranial segment involving middle cerebral artery (L-type), or internal carotid artery intracranial segment involving middle and anterior cerebral arteries (T-type) (including tandem embolic occlusions of the internal carotid artery C1 or common carotid artery); Baseline NIHSS≥6, and meeting local guidelines for mechanical thrombectomy; Time from onset or last known normal to randomization within 24 hours and proceeding to mechanical thrombectomy; Signed informed consent (or by legal representative).
Exclusion: Prior stent implantation in the target vessel that would impede the use or removal of mechanical thrombectomy devices; Pre-stroke mRS score >2; Intracranial hemorrhage shown on imaging; Subjects allergic to contrast agents; Known or suspected internal carotid artery occlusion caused by dissection or atherosclerosis; Vascular tortuosity preventing the use of balloon guide catheter; Any other circumstances impeding mechanical thrombectomy implementation; Acute occlusion of multiple vascular territories in bilateral anterior circulation or in both the anterior and posterior circulations confirmed by CTA/MRA; Pregnant subjects; Subjects refusing to cooperate or unable to tolerate interventional procedures; Subjects whose expected lifetime are less than 90 days; Midline shift or herniation with ventricular mass effect; Subjects deemed unable to participate in follow-up by investigators; Other situations deemed unsuitable for balloon guide catheter use by investigators.