Balloon Guide Catheter Test for Stroke Clot Removal in Carotid Artery Blockages
Tests a balloon catheter during clot removal in adults with stroke.
Plain-language title generated from the registry record
Registry title: Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery
Key facts
- Where
- Beijing, Fuzhou, and Zhangzhou, ChinaSee the 3 sites
Where in China
- Xuanwu Hospital, Capital Medical UniversityBeijing, ChinaTaking people
- Fujian Medical University Union HospitalFuzhou, ChinaTaking people
- Zhangzhou Municipal HospitalZhangzhou, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Xuanwu Hospital, Beijing
- Trial code
- NCT07192029
- Record updated
- 17 November 2025
- Original description
To investigate whether using balloon guide catheter with flow arrest during mechanical thrombectomy, compared to non-flow arrest, improves the rate of first pass expanded Thrombolysis in Cerebral Infarction score (eTICI 2c-3) reperfusion for acute ischemic stroke due to internal carotid artery occlusionRead full original descriptionShow less
Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery: a Randomized Controlled Trial
To investigate whether using balloon guide catheter with flow arrest during mechanical thrombectomy, compared to non-flow arrest, improves the rate of first pass expanded Thrombolysis in Cerebral Infarction score (eTICI 2c-3) reperfusion for acute ischemic stroke due to internal carotid artery occlusion
Inclusion: age ≥18 years; Clinical diagnosis of acute ischemic stroke with internal carotid artery occlusion confirmed by imaging (CTA/MRA/DSA), including isolated intracranial internal carotid artery (I-type), internal carotid artery intracranial segment involving middle cerebral artery (L-type), or internal carotid artery intracranial segment involving middle and anterior cerebral arteries (T-type) (including tandem embolic occlusions of the internal carotid artery C1 or common carotid artery); Baseline NIHSS≥6, and meeting local guidelines for mechanical thrombectomy; Time from onset or last known normal to randomization within 24 hours and proceeding to mechanical thrombectomy; Signed informed consent (or by legal representative).
Exclusion: Prior stent implantation in the target vessel that would impede the use or removal of mechanical thrombectomy devices; Pre-stroke mRS score >2; Intracranial hemorrhage shown on imaging; Subjects allergic to contrast agents; Known or suspected internal carotid artery occlusion caused by dissection or atherosclerosis; Vascular tortuosity preventing the use of balloon guide catheter; Any other circumstances impeding mechanical thrombectomy implementation; Acute occlusion of multiple vascular territories in bilateral anterior circulation or in both the anterior and posterior circulations confirmed by CTA/MRA; Pregnant subjects; Subjects refusing to cooperate or unable to tolerate interventional procedures; Subjects whose expected lifetime are less than 90 days; Midline shift or herniation with ventricular mass effect; Subjects deemed unable to participate in follow-up by investigators; Other situations deemed unsuitable for balloon guide catheter use by investigators.