Comparing two pressure tests for narrowed heart arteries in coronary artery disease
Compares two pressure measurements to assess narrowed heart arteries in adults with coronary artery disease.
Plain-language title generated from the registry record
Registry title: Comparative Analysis of NTG-Pd/Pa and Saline-Pd/Pa (CANS)
Key facts
- Where
- Hsinchu, Miaoli, and Taichung, TaiwanSee the 3 sites
Where in Taiwan
- National Taiwan University Hospital Hsin-Chu HospitalHsinchu, TaiwanNo longer taking part
- Miaoli General Hospital, Ministry of Health and WelfareMiaoli, TaiwanNo longer taking part
- Taichung Veterans General HospitalTaichung, TaiwanNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- National Taiwan University Hospital
- Trial code
- NCT07195968
- Record updated
- 29 September 2025
- Original description
The goal of this observational study is to compare the value of NTG-Pd/Pa and saline-Pd/Pa in participants with intermediate stenosis of the coronary artery. The main questions it aims to answer are:Read full original descriptionShow less
A Prospective, Multicenter Study: Comparative Analysis of NTG-Pd/Pa and Saline-Pd/Pa
The goal of this observational study is to compare the value of NTG-Pd/Pa and saline-Pd/Pa in participants with intermediate stenosis of the coronary artery. The main questions it aims to answer are:
The numerical difference between NTG-Pd/Pa and saline-Pd/Pa To compare the diagnostic performance of NTG-Pd/Pa and saline-Pd/Pa in predicting the binary result of FFR assessment?
Participants will undergo NTG-Pd/Pa, Saline-Pd/Pa, and FFR successively in the target vessel.
Inclusion: Participants with coronary artery with 50-90% stenosis; In participants who suffered from ST elevation myocardial infarction within 5 days, only the non-culprit vessel was eligible for coronary functional testing.
Exclusion: Resting heart rate is less than 50 beats per minute; Heart failure remains decompensated at the time of examination, such as inability to lie flat or cardiogenic shock; Acute onset of asthma or chronic obstructive pulmonary disease; Systolic blood pressure is less than 90 mmHg for more than 5 minutes during examination.