Registry of procedures that adjust heart nerves for fainting and heart rhythm problems
Records outcomes of nerve-targeting heart procedures in adults with fainting-related conditions.
Plain-language title generated from the registry record
Registry title: POLish Registry of CArdioneuroablation and CArdioneuromodulation
Key facts
- Where
- Rzeszów, PolandSee the site
Where in Poland
- SabaMedRzeszów, PolandTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- SABAMED Medical Center Ltd.
- Trial code
- NCT07196397
- Record updated
- 29 September 2025
- Original description
The multicentre observational study POL-CA involves a wide spectrum of patients with a history of syncopy. The study recruits patients with diagnosed vasovagal syndrome, cardioinhibitory carotid sinus syndrome, symptomatic sinus bradycardia or atrioventricular block, postural orthostatic tachycardia syndrome, orthostatic hypotension, and inappropriate sinus tachycardia syndrome. This is an observational, controlled study with retrospective, clinical data analysis of previously treated patients and the analysis of syncopal patients prospectively recruited into the study. The aim of the POL-CA registry is to create a platform for physicians to record treatment data for patients undergoing procedures that affect innervation or modify cardiovascular reflexes (cardioneuroablation, cardioneuromodulation) in order to provide a multicentre summary of population characteristics and treatment outcomes based on a standardized POL-CA questionnaire and methodology for various arrhythmias.Read full original descriptionShow less
POL-CA Registry: Multicenter Observational Study of Neuromodulatory Procedures in Cardiovascular Autonomic Dysfunction Syndromes
The multicentre observational study POL-CA involves a wide spectrum of patients with a history of syncopy. The study recruits patients with diagnosed vasovagal syndrome, cardioinhibitory carotid sinus syndrome, symptomatic sinus bradycardia or atrioventricular block, postural orthostatic tachycardia syndrome, orthostatic hypotension, and inappropriate sinus tachycardia syndrome. This is an observational, controlled study with retrospective, clinical data analysis of previously treated patients and the analysis of syncopal patients prospectively recruited into the study. The aim of the POL-CA registry is to create a platform for physicians to record treatment data for patients undergoing procedures that affect innervation or modify cardiovascular reflexes (cardioneuroablation, cardioneuromodulation) in order to provide a multicentre summary of population characteristics and treatment outcomes based on a standardized POL-CA questionnaire and methodology for various arrhythmias.
Inclusion: Age ≥ 18 years; Diagnosis of at least one of the following conditions:; Inappropriate sinus tachycardia (IST); Postural orthostatic tachycardia syndrome (POTS); Vasovagal syncope (VVS); Cardioinhibitory carotid sinus syndrome (CSS); Symptomatic sinus bradycardia or functional AV block; Orthostatic hypotension (OH); History of recurrent autonomic symptoms (e.g., syncope, bradycardia, palpitations, orthostatic intolerance); Undergoing or previously underwent interventional treatment affecting cardiac autonomic innervation (e.g., cardioneuroablation, SN-sparing ablation, cardiac sympathetic denervation); Provided written informed consent (for prospective arm).
Exclusion: Permanent pacemaker or ICD implanted prior to enrollment; Structural heart disease requiring surgical intervention; Severe psychiatric comorbidities impairing participation; Inability to complete follow-up assessments or questionnaires; Participation in another interventional clinical trial.