Tests ultrasound-guided nerve stimulation to help walking after stroke
Tests added nerve stimulation with physiotherapy in adults recovering from stroke.
Plain-language title generated from the registry record
Registry title: Percutaneous Ultrasound-guided Neuromodulation to Improve Gait Rehabilitation in Patients Who Have Suffered a Stroke.
Key facts
- Where
- Zaragoza, SpainSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07196878, who can take part
Where in Spain
- Universidad de ZaragozaZaragoza, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Alejandro Martín García
- Trial code
- NCT07196878
- Record updated
- 12 June 2026
- Original description
The goal of this clinical trial is to learn if percutaneous ultrasound-guided neuromodulation (NMP-e) can improve gait rehabilitation in adults who have suffered a stroke. The main questions it aims to answer are:Read full original descriptionShow less
Ultrasound-Guided Percutaneous Neuromodulation Protocol to Improve Gait Rehabilitation in Patients Who Have Suffered a Stroke. Clinical Trial.
The goal of this clinical trial is to learn if percutaneous ultrasound-guided neuromodulation (NMP-e) can improve gait rehabilitation in adults who have suffered a stroke. The main questions it aims to answer are:
* Does NMP-e improve walking speed in stroke survivors? * Does NMP-e enhance muscle strength, functional mobility, reduce spasticity, improve balance, and increase health-related quality of life?
Researchers will compare the addition of NMP-e to conventional physiotherapy versus conventional physiotherapy alone to see if the intervention provides additional benefits in gait rehabilitation and other functional outcomes.
Participants will:
* Continue their regular physiotherapy treatment consisting of passive and active-assisted mobilizations and strength exercises. * Receive NMP-e targeting the sciatic nerve at mid-thigh and the common peroneal nerve at the fibular head (experimental group only). * Undergo stimulation with an electrostimulator at 10 Hz for 10 seconds per trial, repeated 10 times, with intensity adjusted for comfort. * Be evaluated before the intervention, immediately after, and one week later using: * 10-Meter Walk Test for gait speed * Dynamometry for ankle plantarflexor and dorsiflexor strength * Time Up and Go test for functional mobility * Modified Modified Ashworth Scale for spasticity * Berg Balance Scale for balance * EuroQoL-5 Dimensions for health-related quality of life
Participants must be adults aged 18-70, able to walk 10 meters without assistance, currently receiving physiotherapy, and able to provide informed consent. Key exclusions include pregnancy, bleeding disorders, needle allergies, systemic inflammatory disorders, or recent invasive physiotherapy.
This randomized controlled trial will be conducted at ATECE, **a Spanish association dedicated to the care and rehabilitation of individuals with acquired brain injury**, where participants will be recruited and receive their interventions. The study aims to evaluate the potential of NMP-e as an adjunctive therapy for improving gait and related functional outcomes in subacute and chronic stroke patients.
Inclusion: Be between 18 and 70 years of age; Have suffered a stroke (CVA); Be in the subacute or chronic phase of the disease; Be able to walk 10 meters without assistance from another person; Currently be undergoing physiotherapy with conservative techniques; Be able to understand the technique being applied; Sign the informed consent form.
Exclusion: Having received invasive physiotherapy treatment in the last 4 weeks; Allergy to needles or metals; Presence of uncontrolled arterial disease; Dermatological disorders; Presence of diseases such as systemic inflammatory disorders (e.g., rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or septic arthritis); Presence of diseases such as tumors, cancer, or metastases; Belonephobia (fear of needles); Presence of uncontrolled coagulopathies; Pregnancy.