"Bimodal vs Unimodal High-Intensity Pulsed Electromagnetic Field Therapy in Older Adults With Knee Osteoarthritis"
Key facts
- Where
- Guadalajara, MexicoSee the site
Where in Mexico
- Hospital Civil de Guadalajara Fray Antonio AlcaldeGuadalajara, MexicoContact: Ana L Villagrana Rodríguez, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Hospital Civil de Guadalajara
- Trial code
- NCT07198750
- Record updated
- 30 September 2025
- Original description
This randomized, double-blind clinical trial aims to evaluate the effect of high-intensity pulsed electromagnetic field therapy (HI-PEMF) applied either exclusively on the knee joint or bimodally on the knee and quadriceps, in older adults with knee osteoarthritis. Both groups will also receive a structured home-based exercise program. The primary outcome is pain reduction, and secondary outcomes include functional performance.Read full original descriptionShow less
Effect of High-Intensity Pulsed Electromagnetic Field Therapy as a Bimodal Intervention for Analgesia and Strengthening in Older Adults With Knee Osteoarthritis: A Randomized Double-Blind Controlled Clinical Trial
This randomized, double-blind clinical trial aims to evaluate the effect of high-intensity pulsed electromagnetic field therapy (HI-PEMF) applied either exclusively on the knee joint or bimodally on the knee and quadriceps, in older adults with knee osteoarthritis. Both groups will also receive a structured home-based exercise program. The primary outcome is pain reduction, and secondary outcomes include functional performance.
Inclusion: Age ≥ 60; Clinical and radiological diagnosis of knee OA grade I-IV; Pain ≥ 3 on Numeric Analog Scale for >6 months; Can walk (with/without aid); Cognitive ability to follow instructions; Signed informed consent; Availability for 9 treatment sessions and home exercise Exclusion Criteria; Prior total knee arthroplasty (unilateral or bilateral); Neurological disorders affecting motor function or cognition (e.g., Parkinson's disease, stroke, moderate to severe dementia); Active inflammatory rheumatic diseases (e.g., rheumatoid arthritis, lupus); Presence of pacemakers, implantable defibrillators, or metallic implants near the treatment area; Current use of other physical therapy modalities for pain (e.g., electrotherapy, ultrasound, TENS) outside the study protocol; Participation in another clinical trial within the past 3 months; Current use of NSAIDs or systemic/local corticosteroids (including intra-articular injections); Open wounds or active infections at the treatment site; Decompensated cardiac conditions or medical contraindication to exercise; Vestibular disorders that affect balance and interfere with functional assessments; Uncorrected visual impairment interfering with gait or balance (visual acuity worse than 20/60 in the better eye, assessed by Snellen chart); Withdrawal Criteria:; Participants who complete fewer than 7 out of the 9 planned intervention sessions (i.e., less than 80% adherence); Occurrence of serious adverse events related to the intervention that contraindicate continuation; Repeated non-compliance with the home exercise program, documented in at least two consecutive weekly follow-up reports; Voluntary withdrawal of consent at any time during the study.