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Tests a faster MRI scan method for people with ischemic stroke

Tests a faster brain MRI scan in adults with ischemic stroke.

Plain-language title generated from the registry record
Registry title: Implementation of New Multimodal MRI Sequences by Fingerprint to Improve Ischemic Stroke Examination.

Key facts

Where
Grenoble, FranceSee the site

Where in France

  • CHU Grenoble AlpesGrenoble, FranceNo longer taking part

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Trial details

Who runs it
University Hospital, Grenoble
Trial code
NCT07199920
Record updated
30 September 2025
Original description
Currently, standard brain MRI takes 20 to 25 minutes, but in the case of ischemic stroke, every minute counts to limit the extension of the necrotic core, with the possibility of recanalizing the occluded artery (intravenous thrombolysis and/or mechanical thrombectomy).Read full original descriptionShow less

Implementation of New Multimodal MRI Sequences by Fingerprint to Improve Ischemic Stroke Examination, a Pilot Study and Proof of Concept

Currently, standard brain MRI takes 20 to 25 minutes, but in the case of ischemic stroke, every minute counts to limit the extension of the necrotic core, with the possibility of recanalizing the occluded artery (intravenous thrombolysis and/or mechanical thrombectomy).

The recent concept of MRI "Fingerprint" (Magnetic Resonance Fingerprinting, MRF) allows the production of a rapid single sequence and the extraction of numerous parameters.

Demonstrating the feasibility and interpretability of multimodal MRI images acquired in MRF would make it possible to consider implementing and, ultimately, replacing conventional sequences, with the aim of shortening acute stroke management times, increasing the number of sequences acquired within a short timeframe (by increasing informativeness), and thus improving patients\' short and long-term vital and functional prognosis.

Inclusion: Age > 18 years; Subacute ischemic stroke patients (< 15 days after onset); Middle cerebral artery or anterior cerebral artery territory stroke; Modified Rankin Scale (mRS) = 0-4.

Exclusion: MRI contraindications.

ClinicalTrials.gov NCT07199920