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An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphoma

Key facts

Where
Beijing, Changchun, Chengdu, Guangzhou, Harbin, Jinan, Langfang, Nanchang, Ningbo, Shanghai, Tianjin, Wenzhou, Wuhan, Xi'an, Yantai, and Zhengzhou, ChinaSee the 20 sites

Where in China

  • Peking University People's HospitalBeijing, ChinaTaking people
  • Peking University Third HospitalBeijing, ChinaTaking people
  • The First Bethune Hospital of Jilin UniversityChangchun, ChinaTaking people
  • West China Hospital of Sichuan UniversityChengdu, ChinaTaking people
  • Guangdong Provincial People's HospitalGuangzhou, ChinaTaking people
  • Harbin Medical University Cancer HospitalHarbin, ChinaTaking people
  • Shandong Cancer HospitalJinan, ChinaTaking people
  • Cancer Hospital Chinese Academy of Medical SciencesLangfang, ChinaTaking people
  • The Second Affiliated Hospital of Nanchang UniversityNanchang, ChinaTaking people
  • The First Affiliated Hospital of Ningbo UniversityNingbo, ChinaTaking people
  • Ruijin Hospital Shanghai Jiaotong University School of MedicineShanghai, ChinaTaking people
  • Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai, ChinaTaking people
  • Chinese Academy of Medical Sciences Hematology Hospital;Lymphoma Diagnosis and Treatment CenterTianjin, ChinaTaking people
  • Tianjin Cancer HospitalTianjin, ChinaTaking people
  • The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, ChinaTaking people
  • Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & TechnologyWuhan, ChinaTaking people
  • Xiehe Hospital, Tongji Medical College Huazhong University of Science & TechnologyWuhan, ChinaTaking people
  • The First Affiliated Hospital of Xian Jiao Tong UniversityXi'an, ChinaTaking people
  • Yantai Yu Huangding HospitalYantai, ChinaTaking people
  • Henan Cancer HospitalZhengzhou, ChinaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Hoffmann-La Roche
Trial code
NCT07200375
Record updated
5 November 2026
Original description
This study will investigate how well glofitamab-based therapy works and how safe it is in Chinese adult participants with relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL).Read full original descriptionShow less

Evaluating Effectiveness and Safety of Glofitamab Based Second-Line Therapy in Chinese Adult Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma: A Prospective, Observational, Multicenter, Cohort Study

This study will investigate how well glofitamab-based therapy works and how safe it is in Chinese adult participants with relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL).

Inclusion: Histologically confirmed R/R DLBCL after one line of systemic therapy; Will be treated with Glofit-based regimen (known as being recommended and having the intention to be treated with Glofitamab at the time of signing ICF) or have initiated Glofit-based regimen treatment within three months (90 days) prior to enrollment.

Exclusion: Participants who currently participate in or plan to participate in any interventional clinical trial.

ClinicalTrials.gov NCT07200375