Sign in

NCT07200739Not yet recruiting

Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)

Development of Deep Learning Models for Detection of Neurodegenerative Diseases Using Speech - a Danish Language-based Artificial Intelligence Study (DetectAI)

Source: ClinicalTrials.gov · Last updated 2 Sept 2026

Brief summary (registry, in English)

The goal of this observational study is to learn if an artificial intelligence (AI)-based speech analysis tool can identify which patients with memory problems need specialist evaluation at a memory clinic. The main questions it aims to answer are: Can the AI model accurately distinguish between patients who need referral to a memory clinic (those with dementia or Mild Cognitive Impairment) and patients who don't (those with normal cognition or memory problems from other causes like depression)? Which speech patterns and cognitive test features are most useful for making this distinction? Researchers will compare speech recordings and cognitive test results from patients diagnosed with dementia or MCI to those from patients with normal cognition or non-neurodegenerative cognitive impairment to see if the AI model can reliably predict who needs specialist dementia care. Participants will: Complete standard cognitive tests at the memory clinic Perform structured speech tasks while being audio-recorded Receive their usual clinical evaluation and diagnosis from memory clinic specialists The results of this study will help develop a tool that can assist doctors in making faster, more accurate decisions about which patients need specialist dementia evaluation, potentially leading to earlier diagnosis and better patient outcomes.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
440 (estimated)
First submitted
23 Sept 2025
Start date
1 Nov 2026
Primary completion date
30 Sept 2028
Lead sponsor
Zealand University Hospital
NCT number
NCT07200739

What you commit to

  • Study type: Observational
  • Planned participants: 440
  • From 1 Nov 2026 to the primary completion date, 30 Sept 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Concomitant diagnoses which are expected to influence cognitive impairment (eg. depression)
  • Patients with concomitant psychosis or severe psychiatric comorbidities other than depression

Other illness

  • Any history of speech or language impairment predating the current condition
    • Cognitively healthy controls:
  • Known diseases which are expected to impair cognitive functions
  • Any history of speech or language impairment predating the current condition
  • Any history of speech or language impairment predating the current condition

Lab values

  • Clinical, laboratory, or neuroradiological findings that could affect cognitive functions

Other

  • Model A:
  • Patients:
  • Significantly impaired vision or hearing (to the extent that the patient cannot participate in the AI analysis)
  • MMSE score \< 16
  • Patients unable to give consent
  • Patients with alcohol consumption \>21 standard alcohol units per week
  • Significantly impaired vision or hearing (to the extent that the patient cannot participate in the AI analysis)
  • MMSE \< 26 and ACE \< 90
  • Patients with alcohol consumption \>21 standard alcohol units per week.
    • Model B:
  • Significantly impaired vision or hearing (to the extent that the patient cannot participate in the AI analysis)
  • MMSE score \< 16
  • Patients unable to give consent

Who the study is looking for

  • Model A (patient participants)
  • Age \> 50 years
  • Fluent in Danish
  • Minimum of 7 years of schooling
  • A diagnosis of either MCI or AD, given at the SUH memory clinic within 6 months before enrollment
    • Model A (cognitively healthy controls)
  • Age \> 50 years
  • Fluent in Danish
  • Minimum of 7 years of schooling
    • Model B:
  • Age \> 50 years
  • Fluent in Danish
  • Minimum of 7 years of schooling

Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Zealand University Hospital
Coordinator of this site? Confirm its status		RoskildeDenmarkUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.