NCT07200882Not yet recruiting
What is the Impact of TKI on Thyroid Function in CML Patients?
Assessment of Tyrosine Kinase Inhibitors on Thyroid Functions in Patients With Chronic Myeloid Leukemia
Source: ClinicalTrials.gov · Last updated 1 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Evaluation of the impact of various TKI on thyroid function in patients diagnosed with cml
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 76 (estimated)
- First submitted
- 23 Sept 2025
- Start date
- 1 Nov 2025
- Primary completion date
- 1 Nov 2027
- Lead sponsor
- Assiut University
- Diseases
- Thyroid cancer, Chronic myeloid leukaemia
- NCT number
- NCT07200882
What you commit to
- Study type: Observational
- Planned participants: 76
- From 1 Nov 2025 to the primary completion date, 1 Nov 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- concomitant use of oral contraceptive pills or corticosteroids.
- Other malignancies requiring concurrent treatment
- previous ttt with TKI
Other illness
- -any history of using drugs interfering with TKI or having effect on thyroid function (Dexamethasone, Phenytoin, Carbamazepine, Rifampin and Phenobarbital)
- Patients with a history of thyroid disease ( hypo or hyperthyroidism or auto immunity )or are already on treatment for thyroid dysfunction
Other
- pregnancy and lactation
Who the study is looking for
- Patients age from 18 to 65 year
- Newly diagnosed CML patients with Philadelphia chromosome positive based on peripheral blood findings and molecular analysis for the BCR-ABL mutation initiating ttt with a TKI (Philadelphia chromosome positive. CML patients )
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.