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NCT07201233Not yet recruiting

Clinical Study on the Safety and Efficacy of Umbilical Cord Blood Infusion in Treating Bone Marrow Suppression .

Clinical Study on the Safety and Efficacy of Unrelated Umbilical Cord Blood Infusion in Treating Bone Marrow Suppression After Chemotherapy in Elderly Patients With Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) .

Source: ClinicalTrials.gov · Last updated 1 Oct 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

The clinical study aims to evaluate the safety and efficacy of umbilical cord blood transfusion in treating bone marrow suppression after chemotherapy in elderly patients with MDS and AML

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
30 (estimated)
First submitted
19 Sept 2025
Start date
1 Nov 2025
Primary completion date
1 Nov 2027
Lead sponsor
Shandong Qilu Stem Cells Engineering Co., Ltd.
NCT number
NCT07201233

What you commit to

  • Study type: Interventional
  • Planned participants: 30
  • From 1 Nov 2025 to the primary completion date, 1 Nov 2027
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • 2)Presence of interstitial lung disease, non-infectious pneumonia, or uncontrolled systemic diseases (such as diabetes, hypertension, pulmonary fibrosis, and acute pneumonia, etc.). Any unstable systemic diseases: including but not limited to unstable angina, cerebrovascular accident or transient ischemic attack (within 6 months prior to screening), myocardial infarction (within 6 months prior to screening), congestive heart failure (New York Heart Association NYHA classification ≥ III,), severe arrhythmias requiring medication, liver, kidney, or metabolic diseases.
  • 4\) Concurrent diagnosis of malignant tumors in other organs;
  • 5\) Concurrent diagnosis of other hematological disorders;

Other illness

  • 3\) Any other uncontrolled active diseases that may interfere with participation in the trial;

Lab values

  • 1\) Other factors that may cause abnormalities in white blood cells and neutrophils, such as concurrent infections, invasive procedures, etc.

Other

  • 6\) Inability to understand or comply with the study protocol;
  • 7\) Individuals deemed unsuitable for participation in this trial by the investigator.

Who the study is looking for

  • 1\) Ages 60-80 years , gender unlimited;
  • 2\) Patients clinically diagnosed with MDS or AML;
  • 3\) Completed chemotherapy and clinically diagnosed with bone marrow suppression grade 2 or above;
  • 4\) Patients with no severe impairment of liver and kidney function (total bilirubin (TBIL): ≤ 1.5×ULN; ALT or AST: ≤ 2.5×ULN; Alkaline phosphatase: ≤ 3×ULN; Serum creatinine: ≤ 1.5×ULN);
  • 5\) Normal cardiac function;
  • 6\) Patients with ECOG 0-2;
  • 7\) Patients or their families have been informed and voluntarily signed a written informed consent form.

Age in the registry: 60 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.