NCT07202793Completed
Effectiveness and Tolerance of Respiratory Rehabilitation in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease
Source: ClinicalTrials.gov · Last updated 2 Oct 2025
Brief summary (registry, in English)
Observational study summary The goal of this observational study is to determine whether an outpatient pulmonary rehabilitation (PR) program-already known to be effective and safe for chronic obstructive pulmonary disease (COPD)-is equally effective and well-tolerated when COPD is complicated by pulmonary hypertension (PH). Main question In adults with COPD + PH, does outpatient PR improve six-minute walk distance (6MWD) and remain safe, to the same extent as in adults with COPD without PH? How the study is conducted Researchers retrospectively analyse medical records from the University Hospital of Poitiers covering a ten-year period. Eligible participants are adults with COPD who completed at least three weeks of supervised PR and underwent echocardiography to assess PH probability. Two cohorts are compared: COPD + PH (intermediate or high echocardiographic suspicion) COPD without PH (no echocardiographic suspicion) Key data collected Change in 6MWD between the start and end of PR (primary endpoint) Proportion of participants achieving a clinically meaningful improvement in 6MWD Occurrence of severe exacerbations (hospital- or emergency-treated events) during the year after PR All-cause mortality within one year Adverse events or program interruptions indicating PR tolerance
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 59 (actual)
- First submitted
- 4 Aug 2025
- Start date
- 1 Sept 2021
- Primary completion date
- 1 Dec 2023
- Lead sponsor
- Poitiers University Hospital
- NCT number
- NCT07202793
What you commit to
- Study type: Observational
- Participants enrolled: 59
- From 1 Sept 2021 to the primary completion date, 1 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Chronic lung disease other than chronic obstructive pulmonary disease or previous lung transplantation
- -,Hospital admission for an acute chronic obstructive pulmonary disease exacerbation in the four weeks preceding rehabilitation
Other illness
- Unstable cardiovascular disease that contraindicates exercise training
- Active cancer with an expected survival under one year
Other
- Pulmonary rehabilitation shorter than three weeks or missing six-minute walk test or echocardiogram data
- Pregnancy at the time of rehabilitation
- Documented refusal to allow medical data to be used for research
Who the study is looking for
- Age 18 years or older
- Spirometry-confirmed chronic obstructive pulmonary disease with a post-bronchodilator FEV1 / FVC ratio below 0 .70
- Completion of at least three consecutive weeks of outpatient pulmonary rehabilitation between January 2013 and December 2023 at the University - Hospital of Poitiers centre
- Six-minute walk test performed within seven days before programme start and repeated during the final week
- Transthoracic echocardiogram carried out within one year before or one year after programme start, used to grade pulmonary hypertension
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Poitiers, University of Poitiers, France Coordinator of this site? Confirm its status | Poitiers | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.