Comparing two anesthesia drug combinations in people with chronic kidney disease
Compares two muscle-relaxing drugs and their reversal drugs during surgery in adults with kidney disease.
Plain-language title generated from the registry record
Registry title: Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease
Key facts
- Where
- Galveston, United StatesSee the site
- Phase
- Phase 4
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07203287, who can take part
Where in United States
- University of Texas Medical BranchGalveston, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- The University of Texas Medical Branch, Galveston
- Trial code
- NCT07203287
- Record updated
- 20 October 2026
- Original description
The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer isRead full original descriptionShow less
Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease
The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease. The main question it aims to answer is
"The use of Cisatracurium with neostigmine leads to less post-operative pulmonary complications than Rocuronium with sugammadex."
Inclusion: The subject is able and willing to provide and sign informed consent; The subject must be between 18 and 80 years of age; The subject should have chronic kidney disease as defined by glomerular filtration rate; The surgery must require general anesthesia with endotracheal intubation and neuromuscular blockade.
Exclusion: Patients presenting for Renal Transplantation; The surgery requires intubation post-operatively; Any patient with end stage renal disease; Documented allergy to Rocuronium, Sugammadex, Cisatracurium or Neostigmine; Any patient under the age of 18; Any patient over the age of 80; Any patient requiring dialysis; Pregnant Female; Any patient in the correctional system; Urgent or Emergent procedure.