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Laparoscopic Partial Splenectomy for Hypersplenism in Liver Cirrhosis Patients

This trial has no sites in United States.

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Trial details

Who runs it
Northern Jiangsu People's Hospital
Trial code
NCT07205471
Record updated
3 October 2025
Original description
In this study,the researchers compared the changes in immune function-related indicators in patients with liver cirrhosis following laparoscopic partial splenectomy,to determine whether this surgical intervention can enhance postoperative immune function and thereby improve patient outcomes.Read full original descriptionShow less

The Clinical Efficacy of Laparoscopic Partial Splenectomy for Hypersplenism in Liver Cirrhosis Patients

In this study,the researchers compared the changes in immune function-related indicators in patients with liver cirrhosis following laparoscopic partial splenectomy,to determine whether this surgical intervention can enhance postoperative immune function and thereby improve patient outcomes.

Inclusion: A clinical, radiological or histologic diagnosis of cirrhosis of any etiology; Splenomegaly with secondary hypersplenism; gastroesophageal variceal bleeding; Informed consent to participate in the study.

Exclusion: Hepatocellular carcinoma or any other malignancy,; Recent peptic ulcer disease; History of Hemorrhagic stroke; Uncontrolled Hypertension; Human immunodeficiency virus (HIV) infection; Child-Pugh grade C; Pregnancy.

ClinicalTrials.gov NCT07205471