Tracks blood pressure changes in people with high blood pressure after renal denervation
Records blood pressure before and one year after renal denervation in adults with hypertension.
Key facts
- Who runs it
- University Hospital, Grenoble
- Where
- La Tronche, FranceSee the site
- Trial code
- Registry title
- Real Life Data From Hypertensive Patients Treated With Renal Denervation in Current Practice in France- French RENal Denervation Registry
- Status
- Recruiting
- People taking part
- 100 people, planned
- Started
- 23 Jun 2025
- Expected to end
- Oct 2028
- Type of study
- Observational
- Record updated
- 3 October 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with high blood pressure who were treated with renal denervation in France. It follows their blood pressure before and 1 year after the procedure.
- Age
- Over 18 years old
- Sex
- All sexes can join
- Disease stage
- High blood pressure (hypertension), treated with renal denervation, whatever the catheter and the reason for the procedure
- Earlier treatment
- Must have been treated with renal denervation in France. Patients already treated in the past may be included.
Main reasons for not taking part
- Renal denervation was not proposed to the patient
- Patient objects to the collection and use of their data for research
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Adult ( > 18 years old) hypertensive patients treated with RDN in France whatever the catheter and the indication. This might include retrospective data for patient already treated with RDN in the past
Who cannot take part
- RDN not proposed to the patient, patient opposing the collection and use of his/her data for research purposes
Where in France
- Chu Grenoble AlpesLa Tronche, FranceContact: Olivier ORMEZZANO, Doctor of medicineTaking people
About the trial
What the trial wants to find out
Renal denervation (RDN) is a recent procedure that can be used to control BP (blood pressure) in hypertensive patients. Numerous publications from randomised trials have demonstrated the efficacy of RDN in this indication. The latest guidelines now include RDN as an effective technique for use in hypertension. Since early 2023, RDN using Medtronic's Spiral radiofrequency system has benefited from transitional authorisation for reimbursement by the French health insurance system. An application for reimbursement is underway for the ultrasound system. We aim to compile an exhaustive prospective register of all procedures carried out in France over the next few years, regardless of the type of catheter used or the context in which the procedure was carried out (transitional reimbursement, industrial register, randomised trial). Our aim is to assess the efficacy and safety of the procedure within the French healthcare system, the characteristics of patients benefiting from the procedure, the centres performing renal denervation, and the care pathways used, and to be able to present all this data, independently of the industry, to the healthcare authorities when it comes time to reassess the value of this procedure and its indications. The goal of this observational study is to learn about changes in blood pressure in patient with high blood pressure before and 1 year after a renal denervation treatment (RDN).
Read full original descriptionShow less
The primary endpoint is to describe changes in systolic blood pressure (SBP) measured by Home Blood Pressure Measurement (HBPM) in patients suffering from high blood pressure, before and 1 year after RDN.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- FRiEND Registry: Real Life Data From Hypertensive Patients Treated With Renal Denervation in Current Practice in France- French RENal Denervation Registry
- Plain-language title
- Tracks blood pressure changes in people with high blood pressure after renal denervationGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 3 October 2025