Tests AI-guided heart pacing against standard pacing in heart failure
Compares AI-guided and standard pacing of the heart in adults with heart failure.
Plain-language title generated from the registry record
Registry title: AI-Guided Left Bundle Branch Area Pacing
Key facts
- Where
- Rochester, United StatesSee the site
Where in United States
- Mayo Clinic in RochesterRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT07206602
- Record updated
- 18 February 2026
- Original description
The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.Read full original descriptionShow less
A Pilot Study Assessing Outcomes Of Artificial Intelligence-Guided Left Bundle Branch Area Pacing For Cardiac Resynchronization In Heart Failure
The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.
Inclusion: Age: 18 years or older; Left Ventricular Ejection Fraction (LVEF): <50% within 6 months prior to enrollment; QRS Duration: Resting QRS duration ≥ 130 ms on ECG OR anticipated right ventricular pacing > 40% OR device in place with right ventricular pacing > 40% within 6 months prior to enrollment; Medical Therapy: Optimized on guideline-directed medical therapy for heart failure; AI-ECG probability of low LVEF: >0.5.
Exclusion: Age less than 18 years old; Inability to follow-up; Pregnancy.