Tests theta-burst magnetic stimulation for treatment-resistant depression
Tests magnetic brain stimulation in adults with depression that has not responded to treatment.
Plain-language title generated from the registry record
Registry title: Effect of Theta-burst rTMS Therapy on the Clinical and Cognitive Symptoms of Patients With Therapy Resistant Depression and Response Prediction With Neuroimaging Methods.
Key facts
- Where
- Budapest, HungarySee the site
Where in Hungary
- Department of Psychiatry and PsychotherapyBudapest, HungaryNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Semmelweis University
- Trial code
- NCT07207239
- Record updated
- 3 October 2025
- Original description
The primary aim of the study is to find the combination of neuroimaging-related markers, demographics, and clinical characteristics that predict the response of patients with therapy-resistant depression to theta-burst rTMS treatment. The secondary aim is to monitor the cognitive effects of TMS therapy.Read full original descriptionShow less
Effect of Theta-burst rTMS Therapy on the Clinical and Cognitive Symptoms of Patients With Therapy Resistant Depression and Response Prediction With Neuroimaging Methods.
The primary aim of the study is to find the combination of neuroimaging-related markers, demographics, and clinical characteristics that predict the response of patients with therapy-resistant depression to theta-burst rTMS treatment. The secondary aim is to monitor the cognitive effects of TMS therapy.
Inclusion: diagnosis of depression; 18 years of age; Beck depression inventory score above 12 (screening); MADRS score above 6 (baseline).
Exclusion: alcohol or drug abuse within the past 3 months; serious cognitive impairment; history of head injury with loss of consciousness for more than 1 hour; mental retardation.