Studies a device therapy for heart failure in patients with reduced heart pumping
Follows people with heart failure treated with a device that strengthens heart contractions.
Plain-language title generated from the registry record
Registry title: Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure
Key facts
- Where
- Marlton, United StatesSee the site
Where in United States
- Impulse DynamicsMarlton, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Impulse Dynamics
- Trial code
- NCT07209098
- Record updated
- 24 March 2026
- Original description
The purpose of this prospective, multi-center, propensity-matched coverage with evidence development (CED) study is to assess the impact of cardiac contractility modulation (CCM) on mortality and heart failure hospitalizations in Medicare-eligible patients with heart failure who meet indications for CCM.Read full original descriptionShow less
Broaden Accessibility of Breakthrough Treatment for Heart Failure: A Prospective, Propensity-Matched CED to Access the Impact of Cardiac Contractility Modulation Therapy (CCM)
The purpose of this prospective, multi-center, propensity-matched coverage with evidence development (CED) study is to assess the impact of cardiac contractility modulation (CCM) on mortality and heart failure hospitalizations in Medicare-eligible patients with heart failure who meet indications for CCM.
Inclusion: Continuous representation in the database in the year prior to index; Age 18 or older will be enrolled in either the treatment or control arm of the study; NYHA III heart failure,; Not receiving CRT; EF 25 - 45%, inclusive; Remain symptomatic despite at least 3 months of optimized guideline-directed medical therapy (GDMT) as determined by the heart team prior to CCM implantation.
Exclusion: Subject has had a prior heart transplant; Subject with mechanical tricuspid valve; Subject has a left ventricular assist device (LVAD).