Tests two reading therapies in adults with acquired dyslexia after stroke
Compares two reading therapies in adults with reading loss after stroke.
Plain-language title generated from the registry record
Registry title: Acquired Dyslexia Modeling and Treatment
Key facts
- Where
- Baltimore, Tallahassee, and West Orange, United StatesSee the 3 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 85 years old?
Source: NCT07209488, who can take part
Where in United States
- Johns Hopkins University School Of MedicineBaltimore, United StatesTaking people
- Florida State UniversityTallahassee, United StatesTaking people
- Kessler FoundationWest Orange, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Rutgers, The State University of New Jersey
- Trial code
- NCT07209488
- Record updated
- 6 May 2026
- Original description
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.Read full original descriptionShow less
Evidence-based Modeling for Acquired Dyslexia Treatments
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.
Inclusion: Fluent in English as a first language pre-stroke by self report; Normal or corrected-to-normal vision; Normal or aided hearing; Left hemisphere ischemic or hemorrhagic stroke (as verified by a structural brain scan); Impaired reading as confirmed by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III.
Exclusion: Diagnosed pre-stroke neurological disease affecting the brain other than left hemisphere stroke; History of learning disabilities such as developmental dyslexia or current self-reported major psychiatric disorders; Inability to undergo, or provide a copy of, a post-stroke brain imaging scan; Severe apraxia of speech (determined by consensus judgment among speech-language pathologists).