Diet Plan to Relieve Constipation in People With Parkinson's Disease
Tests a dietitian-guided diet plan for constipation in adults with Parkinson's disease.
Plain-language title generated from the registry record
Registry title: Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease
Key facts
- Where
- Porto Alegre, BrazilSee the site
Where in Brazil
- Hospital de Clínicas de Porto Alegre - HCPAPorto Alegre, BrazilTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital de Clinicas de Porto Alegre
- Trial code
- NCT07213856
- Record updated
- 16 June 2026
- Original description
The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD). The main questions it aims to answer are:Read full original descriptionShow less
Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease: A Randomized Clinical Trial
The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD). The main questions it aims to answer are:
* Can a dietitian-guided nutritional intervention increase the number of weekly bowel movements in individuals with PD and functional constipation? * Can this intervention positively influence gut microbiota composition, dietary intake, and nutritional status?
Researchers will compare the intervention group to a control group that will receive general dietary guidance only after the study period, to see if the intervention leads to improvements in bowel function and related health outcomes.
Participants will:
* Follow a diet plan developed by a dietitian, based on dietary reference intakes and tailored to the needs of individuals with PD and constipation * Participate in follow-up sessions with the dietitian for 3 months * Complete assessments at baseline, midpoint, and end of the intervention to evaluate bowel function, constipation symptoms, gut microbiota, nutritional status, and diet quality
Inclusion: Adults with a previous diagnosis of Parkinson's disease; On a stable dose of levodopa for at least 3 months; Diagnosis of Functional Constipation by the Rome IV protocol.
Exclusion: Previous diagnosis of dementia; Individuals receiving enteral or parenteral nutrition; Presence of severe neurological or psychiatric disorders that impair the ability to participate in study procedures; Presence of comorbidities such as active cancer, chronic obstructive pulmonary disease (COPD), heart failure, and/or chronic kidney disease; History of gastrointestinal cancers, inflammatory bowel diseases, or surgeries involving the gastrointestinal tract; Constipation secondary to clinical conditions such as hypothyroidism or diabetes mellitus; Diagnosis of atypical or secondary parkinsonism; Hoehn and Yahr stage greater than 2; Use of opioids; Use of probiotics or antibiotics in the past 8 weeks; Continuous use of laxatives in the past 8 weeks; Presence of severe dysphagia according to the Functional Oral Intake Scale (FOIS); Individuals under nutritional follow-up in the past 3 months.